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Solutions for AAV Research & Development: AAV Titration and Anti-AAV Antibody ELISA Kits
Product Description:
Adeno-associated virus (AAV) vectors have emerged as a pivotal tool in gene therapy, offering a promising delivery system in treating genetic disorders. As AAV vector applications in gene therapy continue to expand, the need for precise and reliable tools to support research and development become increasingly critical. Two fundamental aspects of AAV research are the accurate quantification of AAV capsid titters and the detection of pre-existing antibodies against AAV. These measurements are essential for ensuring safety, efficacy, and proper dosing of gene therapies, as well as facilitating the successful translation of gene therapies from the laboratory to clinical applications.
The AAV Titration ELISA Kit provides precise quantification of AAV capsids in a biological sample, critical for determining correct therapeutic dosages and maintaining production QC. This kit ensures reliable measurements, optimizing production processes and meeting regulatory standards for clinical applications.
Product List:
AAV5 Titration ELISA Kit
AAV8 Titration ELISA Kit
AAV3 Titration ELISA Kit
AAV2 Titration ELISA Kit
AAV9 Titration ELISA Kit
Product Features:
- Strong specificity: No cross-reactivity with other AAV serotypes.
- High sensitivity: Detects as low as 1.70E+08 capsids/mL.
- Wide detection range: Covers 1.70E+08 to 1.09E+10 capsids/mL.
- Rapid detection: Results available in just 2 hours and 20 minutes.
- High accuracy: Sample recovery rates range from 80% to 120%.
- Rigorous validation: Comprehensive validation reports are available.
Pre-existing antibodies against AAV vectors present a significant challenge to AAV-mediated gene therapy, potentially compromising treatment efficacy in both human patients and animal models. Anti-AAV Antibody ELISA Kits provide quantitative, reproducible results crucial for establishing antibody titer thresholds that may impact treatment outcomes.
Product List:
Anti-AAV5 Antibody ELISA Kit
Anti-AAV8 Antibody ELISA Kit
Anti-AAV9 Antibody ELISA Kit
Anti-AAV2 Antibody ELISA Kit
