Therapeutic Targets for Neurodegenerative Diseases

Neurodegeneration is a neurological disorder with evolving atrophy and irreversible damage of neurons. Alzheimer's (AD) and Parkinson's (PD) are two of the most common neurodegenerative diseases. GDNF, NGF, and BDNF are growth factors responsible for the survival, maintenance, and regeneration of specific neurons, rendering them as therapeutics for neurodegenerative diseases.

Clinical trials of GDNF (therapy for PD), NGF (therapeutic option for AD), and BDNF (therapeutic target for both AD and PD) are in progress. Therapies targeting neurotrophic factors and associated receptors can also be an effective approach for the less common neurodegenerative diseases such as Huntington's (HD), amyotrophic lateral sclerosis (ALS), and Rett Syndrome.

Sino Biological has developed a panel of high-quality recombinant GDNF, NGF, and BDNF to support the research for neurodegenerative diseases.