Cell Culture – News and Features

Endometrial organoids, 3D cell cultures mimicking the endometrium, offer new opportunities in endometriosis research. These models are key in studying drug targets, fertility issues and gynecological cancers.

New research has provided insight into the biological mechanisms that may contribute to poor outcomes in certain cases of neuroblastoma – a cancer that develops in nerve tissue and primarily affects children.

A study reveals mitochondrial dysfunction in lymphoblast cell lines (LCLs) from children with Dravet syndrome. These cells exhibited reduced energy production, providing insights into the condition’s neurological symptoms.

ETH researchers discovered related structures in Asgard archaea and describe their structure. These experiments show that Asgard tubulins form very similar microtubules, albeit smaller than those in their eukaryotic relatives.

One of the key challenges of the modern genomics era is studying the thousands of genes in a single human cell at scale. To overcome this, scientists have developed PERISCOPE, which combines the power of microscopy imaging with CRISPR screening.

Researchers are studying how exercise influences breast cancer progression. Their findings show that physical activity can lower estrogen levels, regulate metabolic markers, reduce chronic inflammation and boost immune responses.

The integration of AI and automation is transforming laboratory research, improving overall efficiency and scalability. However, scientists must be cautious as over-reliance on AI may weaken critical thinking and troubleshooting skills.

Researchers discovered that Zika virus constructs nanotubes to transport infection across the placental barrier undetected. The viral protein NS1 triggers this process, allowing Zika to spread while evading immune defenses.

Epithelial cells "talk" to each other with slow electrical signals, and "scream" to their neighbors when injured, new research has discovered.

Researchers have developed pig retinal organoids to understand how stem cell-derived photoreceptor cells work as a therapeutic.