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CRISPR and Genome Editing – News and Features

Microscopic imaging of blood vessels.

Blood Vessel Protein Linked to Drug-Resistant Cancer

Researchers clarify the role of an elusive angiocrine factor in the tumor microenvironment and its effect on cancer stem cells. Further research will serve as a stepping stone to effective therapies for drug-resistant cancer.
Gloved hand using tweezers to remove a test tube from liquid nitrogen.

Overcoming Obstacles in Automating Cryogenic Storage

This article explores the challenges and strategies involved in transitioning to automated cryogenic storage systems. From assessing current infrastructure to gaining organizational buy-in and selecting appropriate containers, follow these steps to help ensure a successful transition to automated cryogenic storage.
Three red tomatoes on a vine.

Researchers Breed Tomatoes That Contain Total Genetic Material of Both Parents

Tomatoes that contain the complete genetic information of both parents could ensure that beneficial traits are passed down through generations.
Bacteria with tails.

Unique Immune Component Allows Deadly Strain of Cholera To Out-Compete Other Variants

The persistence of a deadly strain of cholera that emerged in 1961 has baffled scientists. New research has shown how it has managed to out-compete other variants.
A man in t-shirt and shorts runs along a path.

Experimental Drug Makes Exercise Easier for People With Common Heart Condition

An experimental drug can increase oxygen uptake in people with hypertrophic cardiomyopathy, making it easier for them to exercise and carry out day-to-day tasks.
A scanning electron microscope image of virion.

Gene Therapy Eliminates 90% of Herpes Infection in Mouse Models

Preclinical studies of a new gene therapy show it can eliminate 90% or more of herpes infection and suppress how much virus can be released by an individual.
Double helix structure of DNA.

Novel Epigenome Editing Platform Unravels Gene Regulation Mechanisms

A study from the Hackett group at EMBL Rome led to the development of a powerful epigenetic editing technology, which unlocks the ability to precisely program chromatin modifications.
A cancer cell is attacked by T cells.

CAR T-Cell Therapy Could Be Adapted for Solid Tumors, Study Finds

CAR T-cell therapy could be adapted to target solid tumors, potentially transforming cancer treatment.
Cancer cells.

New Potential Target for Leukemia Therapy Identified

A team of Dana-Farber Cancer Institute investigators discovered that a subset of myeloid and lymphoid leukemias depend on a molecular complex called PI3Kgamma for survival.
Two researchers in a lab.

CRISPR Gene Editing Therapy Improved Vision in Trial for Inherited Blindness

Results from a clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show that the treatment is safe and led to measurable improvements in 11 of the participants treated.