Drug Kinetics – News and Features

Scientists have developed a new type of nanoparticle made from a medical polymer and blood protein that can carry larger amounts of disease-fighting drugs and remain stable for longer than current alternative nanoparticle systems.

Solvent polarity plays a critical role in determining how effectively drugs can be loaded into metal-organic framework (MOF) carriers, a new study has found. This previously overlooked factor could help to improve drug delivery.

The STARLYNG-1 trial tested a weekly oral version of risperidone for schizophrenia, showing it maintains therapeutic drug levels and reduces side effects. The study found that the weekly pill may help improve medication adherence.

Researchers have used electrospinning to produce polymer mats containing the antibacterial drug metronidazole. These mats could be used as active wound dressings, as their structure lets them release drugs in a controlled manner.

A protein that gives fleas their bounce has been used to boot out bacteria cells, with lab results demonstrating the material’s potential for preventing medical implant infection.

A new method for targeted drug delivery uses chemically tagged platelets, offering fast, efficient treatment with minimal long-term drug presence.

Researchers evaluated data from women who had recently been diagnosed with breast cancer. The study confirmed that those with lower muscle mass at the start of the follow-up period had a worse prognosis than those with normal muscle mass.

The Blood In situ Tracking (SENSBIT) system remained fully functional for up to a week when implanted directly into the blood vessels of live rats.

Discover the latest in cystic fibrosis treatment, from CFTR modulators to ENaC blockers and emerging inhalable gene therapies.

Scientists have engineered a new type of sensor to monitor substances in the body over long stretches – measuring reactions for up to a week after being implanted in living rats.