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Drug Kinetics – News and Features

This digitally-colorized, negative-stained transmission electron microscopic (TEM) image depicted a number of Influenza A virions.

Drug-Like Molecule Shows Promise in Preventing Flu Infection

Scripps Research scientists have developed a potential drug-like molecule that blocks the first stage of type A influenza infection. The drug-like inhibitors block the virus from entering the body’s respiratory cells.
Cancer cells.

Mouse Study Explores Why Glioblastoma Treatment May Work Better in the Morning

Glioblastoma is an aggressive brain cancer that has no cure. A recent chart study of patients with glioblastoma found that taking chemotherapy in the morning was associated with a three- to six-month increase in median survival.
Two researchers at a whiteboard.

Physicists Propose Path to Faster, More Flexible Soft Robots

Physicists have revealed a microscopic phenomenon that could greatly improve the performance of soft devices, like flexible robots or microscopic capsules for drug delivery.
A scientist pipetting into a test tube.

Study Sheds Light on Preventing PXR-Associated Drug Resistance

Scientists at St. Jude Children’s Research Hospital uncovered a route to blocking activity of protein notorious for eliminating drugs, offering a potential boon to cancer therapy.
Double helix structure of DNA.

Designing Peptoids That Mimic Nature’s Helices

Nature is filled with extraordinarily precise molecular shapes that fit together like a hand in glove. Proteins, for example, can assemble into a wide variety of well-defined shapes that grant them their function.
An individual holding up a piece of hair that has come out of their head.

Microneedle Patch Offers Hope for Alopecia Areata Treatment

Researchers developed a potential new treatment for alopecia areata, an autoimmune disorder causing hair loss. The new microneedle patch delivers immune-regulating molecules that can teach T cells not to attack hair follicles, helping hair regrow.
The crystal structure of a lattice.

“Better Than Graphene” Material May Improve Implantable Technology

The atomically thin version of boron, borophene, has been made chiral to enable it to interact in unique ways with biological units.
An alarm clock.

Circadian Rhythms Impact Drug Effectiveness

Using tiny, engineered livers derived from human patients, researchers found that more than 300 liver genes are under circadian control. These circadian variations affect how much of a drug is available and how effectively the body can break it down.
Schematic representation of SemaCyte microcarriers including optical barcodes.
Industry Insight

Tackling Unmet Drug Screening Needs

In this interview, Jeroen Verheyen tells us about Semarion, its SemaCyte technology and how it can help to address unmet drug screening needs.
A close up of a patients hand attached to a tube feeding medicine.

New Closed-Loop Drug Delivery System Could Improve Chemotherapy

To make chemotherapy dosing more accurate, MIT engineers have come up with a way to continuously measure how much drug is in the patient’s system during the hours-long infusion.