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Drug Kinetics – News and Features

A person holding some kale, a source of the natural antioxidant kaempferol.
News

Natural Antioxidant Slows Nerve Cell Damage in Cells From ALS Patients

In lab-grown nerve cells from ALS patients, a natural compound found in certain fruits and vegetables helped the cells produce more energy and eased stress in the protein-processing center of the cell called the endoplasmic reticulum.
A person holding pain medication in their hands.
News

Novel Pain Relief Drug Could Offer Safer Alternative to Opioids

University of Florida scientists have helped identify a novel drug compound that selectively activates pain-altering receptors in the body, offering a potentially safer alternative to conventional pain medications such as opioids.
A group of drugs in front of MRI scans of the human brain, representing drug delivery to the brain.
News

Nanoparticles Deliver Anti-Inflammatory Medicine to the Brain

Oregon State University researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of neurodegenerative diseases.
Human cell models floating in a fluid environment, showcasing detailed transparent membranes and vibrant purple nuclei.
Article

Bridging the Gap: Creating More Physiologically Relevant Human Cell Models

Three-dimensional models allow researchers to better represent complex tissues and cell-cell interactions. This article explores the cell models currently used by researchers to understand disease and aid drug discovery.
Visualization of the small and large intestines showing a range of bacteria, representing the gut microbiome.
News

Could Your Gut Microbiome Make Certain Drugs Less Effective?

New findings on how the gut microbiome influences drug metabolism and effectiveness could open the door to personalized medicines and better treatment outcomes.
An orange cancer cell against a blue background with a target on it, illustrating targeted drug delivery.
News

Researchers Scale Up Manufacture of Nanoparticles for Drug Delivery

MIT researchers have developed a way to rapidly manufacture specialized nanoparticles that can be used for targeted delivery of cancer drugs and other therapeutics.
3D rendered image of cancer cells dividing.
News

Drug-Delivering DNA Aptamers Target Elusive Leukemia Stem Cells

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report.

A single strand of mRNA used in RNA therapeutics such as COVID-19 mRNA vaccines.
Article

The Future of RNA Therapeutics, From Design to Delivery

Discover how RNA therapeutics are reshaping medicine, offering new treatments for previously undruggable targets.
A close-up of a lipid nanoparticle, showing the phospholipid bilayer.
News

Novel Phospholipids Enhance mRNA Drug Delivery

A study conducted by researchers at Hokkaido University has unveiled a novel class of zwitterionic phospholipids capable of significantly enhancing the functional delivery of mRNA.
A close-up of a mosquito biting human skin.
News

Repurposed Rare Disease Drug Makes Blood Deadly to Mosquitoes

Nitisinone, a medication typically prescribed for individuals with rare inherited diseases, has been shown to make human blood deadly to mosquitoes. It could therefore be an alternative method for controlling mosquito populations.
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