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Drug Kinetics – Webinars and Online Events

Feel the Need, the Need for Speed: Advances in RapidFire-MS Analyses for Faster, Larger Runs with Less Sample Presentation Session 1 content piece image
Webinar

Feel the Need, the Need for Speed: Advances in RapidFire-MS Analyses for Faster, Larger Runs with Less Sample Presentation Session 1

On-Demand
We will explore how these advances are being utilized, both individually and in tandem, as we discuss a variety of new applications demonstrating the benefits of this improved, fully integrated system.
From Dose to Circulation – Determination of Drug Oral Bioavailability Using a Gut–Liver Microphysiological System content piece image
Webinar

From Dose to Circulation – Determination of Drug Oral Bioavailability Using a Gut–Liver Microphysiological System

On-Demand
In this webinar, Dr. Yassen Abbas will discuss how CN-Bio’s gut–liver MPS can be used for in vitro determination of oral bioavailability.
Advances in Drug Discovery and Development 2021 content piece image
Online Event

Advances in Drug Discovery and Development 2021

On-Demand
Accessed via mobile, tablet or PC, this inaugural free-to-attend event will provide those working within academia and pharmaceutical development the opportunity to hear from experts within the field. Focus will be given to the latest advances in small molecule drug discovery and development, biopharma and biotechnology.
Liver-on-Chip and <i>In Silico</i> Modeling for Quantitative Drug Metabolism Studies content piece image
Webinar

Liver-on-Chip and In Silico Modeling for Quantitative Drug Metabolism Studies

On-Demand
This webinar will examine the benefits of combining LOAC with in silico modeling to explore clinical PK predictions of specific reference drugs, including investigations into the intrinsic clearance determinations for high metabolically stable compounds and the quantitation of fractions metabolized by specific enzymes.
Bringing Life to PK Profiles – <i>In Vivo</i>-Relevance From an <i>In Vitro</i> Environment content piece image
Webinar

Bringing Life to PK Profiles – In Vivo-Relevance From an In Vitro Environment

On-Demand
In drug development, microphysiological systems (MPS) are utilized to develop in vitro biological models that can generate more physiologically- and human-relevant data.
Formulating a New Approach to Pharmacokinetics and Cell State Control content piece image
Webinar

Formulating a New Approach to Pharmacokinetics and Cell State Control

On-Demand
Most in vitro, well-plate biological experiments require a media change every day or two, with cyclic variations in nutrient and metabolite concentrations leading to physiologically unrealistic gene expression and metabolism.
Towards a Body-on-a-Chip: The Value of Multi-Organ MPS for Human-Relevant Drug Assessment content piece image
Webinar

Towards a Body-on-a-Chip: The Value of Multi-Organ MPS for Human-Relevant Drug Assessment

On-Demand
Microphysiological Systems (MPS), also known as organ-on-a-chip, generate human-relevant 3D cell culture models whose phenotypes and functions mimic individual in vivo organs. When therapeutics are added, these models can generate results that translate into clinical outcomes more reliably than standard in vitro techniques.
Testing on Humans: How To Predict Hepatotoxicity and Drug Clearance Ahead of Clinical Trials Using Liver-on-a-Chip content piece image
Webinar

Testing on Humans: How To Predict Hepatotoxicity and Drug Clearance Ahead of Clinical Trials Using Liver-on-a-Chip

On-Demand
Current in vitro approaches for investigational toxicology, drug metabolism (DMPK) and safety are limited and are not fully representative of human response; therefore, drugs showing acceptable preclinical toxicity often fail in human clinical trials, and accurately predicting human drug exposure for new compounds is challenging and costly.
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