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Gene and Cell Therapy – Multimedia

5 Films that get Biology all Wrong content piece image
Listicle

5 Films that get Biology all Wrong

Here we take a look at 5 films that get biology very wrong.
A Novel Set of Serum-Free, Xeno-Free Differentiation Media for Adipogenesis, Osteogenesis and Chondrogenesis of Human Mesenchymal Stem Cells from Various Tissue Sources content piece image
Poster

A Novel Set of Serum-Free, Xeno-Free Differentiation Media for Adipogenesis, Osteogenesis and Chondrogenesis of Human Mesenchymal Stem Cells from Various Tissue Sources

An overview of a novel SF, XF differentiation system which enables achieving defined conditions for rapid generation of differentiated hMSCs towards tissue engineering and drug screening applications.
Cardiac iPSCs for Drug Discovery content piece image
Video

Cardiac iPSCs for Drug Discovery

Video

Cardiac iPSCs for Drug Discovery

Joseph Wu, Director, Stanford Cardiovascular Institute, speaking at Stem Cells in Drug Discovery.
Pharmacological Responses in Cultured Human iPSC-Derived Cortical Neurons Using Multi-Electrode Array   content piece image
Poster

Pharmacological Responses in Cultured Human iPSC-Derived Cortical Neurons Using Multi-Electrode Array

The functional network of human induced pluripotent stem cell (hiPSC)-derived neurons is a potentially powerful in vitro model for evaluating disease mechanisms and drug responses. However, the culture time required for the full functional maturation of individual neurons and networks is uncertain. We investigated the development of spontaneous electrophysiological activity and pharmacological responses for over 1 year in culture using multi-electrode arrays (MEAs).
Video

A Novel Vertically-Integrated Platform for the Discovery and Molecular Characterization of Lung Cancer Stem Cells

Raj Batra, University of California Los Angeles, speaking at Diagnostics & Biomarkers 2015.
Efficacy of Gene Therapy in Restoring Vision in Leber's Congenital Amaurosis content piece image
Poster

Efficacy of Gene Therapy in Restoring Vision in Leber's Congenital Amaurosis

The research reviews current knowledge of the genetic causes of Leber's congenital amaurosis (LCA) and the development of a gene therapy intervention for LCA. The efficacy as well as the limitations of this form of treatment are evaluated in detail and recommendations are made for the future directions of gene therapy for Leber's congenital amaurosis.
Gene Expression from Pseudourine and 5-Methylcytidine Modified Messenger RNA content piece image
Poster

Gene Expression from Pseudourine and 5-Methylcytidine Modified Messenger RNA

Study objective was to develop methodologies for gram scale synthesis of messenger RNA (mRNA) for gene therapy applications, as well as scalable purification methods that yield highly expressed, persistent and non-toxic mRNA.
Defining off-target cleavage in a pair of Zinc Finger Nucleases content piece image
Poster

Defining off-target cleavage in a pair of Zinc Finger Nucleases

This study looks at off-target cleavage of Zinc Finger Nucleases (ZNFs) in Drosophila in an attempt to analyze potential cleavage spots, with a view to designing more efficient ZFNs.
Regulatory requirements in the development of advanced therapy products (cell-, gene therapy, tissue engineering products) content piece image
Poster

Regulatory requirements in the development of advanced therapy products (cell-, gene therapy, tissue engineering products)

Regulatory authorities are active to ensure a good regulatory environment for somatic cell therapy-, gene therapy- and tissue engineering products (in the EU known as ‘Advanced Therapy Medicinal Products’). Both the EMEA and the FDA have, amongst others, issued guidelines to address the specific aspects of these products
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