Infectious Diseases – News and Features

A novel lysosomal strategy shows potential for inhibiting virus infection in cell and lung organoid models.

Brigham and Women’s researchers uncover bile’s dynamic role in intestinal infection defense, revealing compositional changes that enhance gut protection. Using a mouse model, they identified over 800 bile metabolites altered by pathogens.

Researchers have identified that the SARS-CoV-2 spike protein accumulates in the brain's protective layers, potentially explaining the neurological symptoms of long COVID.

Researchers uncovered a novel bacterial resistance strategy where E. coli modifies ribosomal structures to evade antibiotics like streptomycin and kasugamycin. Using nanopore sequencing, the study revealed ribosomal changes that prevent effective dru

Researchers have identified two fungal enzymes that hijack the immune system of plants and colonize their root systems.

A study identifies "proteolethargy," reduced protein mobility caused by oxidative stress, as a unifying mechanism in chronic diseases. The findings suggest that impaired protein movement disrupts cellular functions.

A study reveals genetic markers for sex determination in cattle fever ticks, paving the way for genetic pest control strategies. This could lead to environmentally sustainable solutions for combating ticks and their associated diseases.

Researchers have found that DNAN, used as a TNT replacement in explosives, is toxic to plants and accumulates throughout their tissues. Unlike TNT, DNAN lingers longer and lacks natural detoxification mechanisms.

A study from MUSC Hollings Cancer Center shows a 62% drop in cervical cancer deaths among women under 25, attributed to HPV vaccination. Despite this success, HPV vaccination rates remain below target, with only 60% of adolescents vaccinated.

Lenacapavir, an injectable PrEP taken twice a year, demonstrated 96% efficacy in preventing HIV infections in a global Phase III trial. The study revealed higher adherence and effectiveness compared to daily oral PrEP.