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Multiomics – News and Features

A girl sitting on a chair looking out a window.
News

PTSD and Depression Have Shared and Distinct Brain Molecular Dysregulations

McLean Hospital researchers uncovered both shared and distinct molecular changes across brain regions, genomic layers, cell types and blood in individuals with posttraumatic stress disorder (PTSD) and major depressive disorder (MDD).
Two doctors stitching a patient after surgery
News

How Cells React to Pig Heart and Kidney Transplants in Humans

Two new studies reveal changes at the single-cell level in the organs and recipients’ bodies before, during and after transplantation with genetically modified pig organs in decedents.
Microbes in the gut.
News

Gut Bacteria Boosts Cancer Immunotherapy in Mice

A new strategy uses gut microbes to help unlock immunotherapy’s untapped cancer-fighting potential.
A woman on a mat doing sit ups.
News

The Effects of Exercise Revealed at the Cellular Level

Prolonged physical activity in rats results in profound changes to RNA, proteins, and metabolites in nearly all tissues, providing clues to many human health conditions.
Dr. Sarah Teichmann standing next to a building and pond.
Article

From School Science Club to Cell Atlasing With Dr. Sarah Teichmann

In this interview, Dr. Sarah Teichmann shares insights into her research interests, the goals and progress of the HCA to date, as well as her thoughts on how women can begin and build successful careers in science.
Cancer cells.
News

Biomarkers Linked to Cell Therapy Response for Bone Marrow Tumors Identified

In a recent clinical study, researchers identified several biomarkers that are associated with the response to CAR T cell therapy in multiple myeloma, a malignant tumour disease in the bone marrow.
A 3D model of human lungs.
News

Harmless Particles Found To Improve Immune Response

The immune system trains its response whenever it encounters such a pathogen. Yet researchers at the University of Bonn have now shown that even harmless particles help to improve the immune response.
Illustration of a human form
Article

Dissecting the Proteome To Understand Disease

Proteomics provides insights into the regulation of biological processes and mechanisms of disease. In this article, we explore approaches scientists are using to find early markers of disease, new drug targets and strategies to overcome resistance to treatments.
Oak tree on a white background.
Industry Insight

Sequencing Life To Conserve Biodiversity

Neil Ward tells us about the role that genomics can play in conserving biodiversity and how innovative technologies such as HiFi sequencing are helping biodiversity projects.
Dr. Khadijah A. Mitchell
Article

Cancer Research, Mentorship and Confidence in Your Competence With Dr. Khadijah A. Mitchell

Cancer researcher Dr. Khadijah A. Mitchell reflects on her journey into studying health disparities, touches on the importance of mentorship and shares some inspiring advice for women and girls considering a career in STEMM.
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