Multiomics – News and Features

We spoke to physician–scientist Professor Pradipta Ghosh about what drove her to follow this career path, her current work, the value of and challenges faced by physician–scientists and advice for those who are considering following in her footsteps.

New research shows potential for DNA methylation, an epigenetic marker, in understanding how genetics and lifestyle factors influence dementia risk.

Researchers have developed a method to isolate and analyze microglia phagosomes in a rapid, gentle, and unbiased fashion. They also share new insights regarding synaptic pruning and generation of NAD+, a broadly used molecule in the brain, by microglia.

A new study has identified diet-derived metabolites, associated with red and processed meats, that drive young-onset colorectal cancer risk.

If it’s ever felt like everything in your body is breaking down at once, that might not be your imagination. A new Stanford Medicine study shows that many of our molecules and microorganisms dramatically rise or fall in number during our 40s and 60s.

The new study identifies 4,248 CpG sites associated with the risk of seven different types of cancer: breast, colorectal, renal cell, lung, ovarian, prostate and testicular germ cell cancers.

A new metabolome-informed proteome imaging (MIPI) workflow has been developed for studying microscale microhabitats in complex ecosystems, opening the door to novel explorations and applications in both environmental and clinical settings.

ACE, a new DNA-powered signal amplification technology, dramatically increases sensitivity of mass cytometry, opening new windows on many biological and pathological processes.

A bitter taste is traditionally considered a warning sign of potentially toxic substances. But not all bitter substances are harmful. A new study now offers the first explanation for this seemingly paradoxical phenomenon.

Researchers have uncovered surprising strategies for how dengue and hundreds of other viruses replicate in their hosts. These findings offer new hope in the search for novel antiviral treatments and vaccines against dengue viral infections.