Neurodegeneration – News and Features

A series of digital tests, carried out via a smartphone app, could enhance the detection of disease progression in Huntington’s disease and improve the efficiency of clinical trials.

A study from King’s College London links gut bacteria changes to cognitive decline in Parkinson’s disease. The research suggests that oral-gut translocation, where harmful bacteria move from the mouth to the gut, may contribute to symptoms.

A gut-derived compound called propionate may slow the progression of Alzheimer's disease by reducing inflammation and plaque build-up in the brain, new research in mice suggests.

University of Connecticut School of Medicine study published in PNAS introduces Healthspan Proteomic Score as a biomarker for healthy aging.

The findings, published in Neurology, suggest that changes associated with ageing may occur earlier than previously recognized in this population.

Estradiol, the most potent form of estrogen during a woman’s reproductive years, may help protect the brain as it ages, as a new study finds that women with a longer reproductive span showed signs of slower brain aging.

Researchers have discovered a novel biomarker for severe multiple sclerosis (MS). This research will contribute to our understanding of the molecular processes involved in progressive MS, and may aid in the allocation of patients to novel therapies.

Dr. John Beeler, BPGbio, discusses why investing in biology is essential for AI-driven drug discovery and for building a more sustainable, cost-effective healthcare system worldwide.

Researchers bring new understanding to how unfoldases and deubiquitinating enzymes coordinate to regulate protein degradation, and how this may influence neurodegenerative diseases and cancer.

The FDA’s approval was supported by two Phase 3 clinical studies, which showed that the ENCELTO implant slowed the loss of light-sensing retinal cells in people with macular telangiectasia type 2 over a 24-month period.