Neurodegeneration – News and Features

Tiny cells inside small blood vessels called pericytes can be forced to change shape and create "cellular bridges" that support axon regeneration after spinal cord injury.

A study identifies a genetic link between autism and myotonic dystrophy type 1 (DM1). Researchers found that tandem repeat expansions in the DMPK gene, causing DM1, also disrupt gene splicing in the brain.

A UT Southwestern study finds that higher cardiorespiratory fitness may slow age-related brain atrophy, preserving cognitive function. The study showed that those with better physical fitness had larger brain volumes and better cognitive performance.

A long-term study reveals how age, sex, genetics, and menopause influence blood biomarkers related to dementia. The study tracked neurofilament light chain proteins, glial fibrillary acidic proteins, and phosphorylated tau 181.

Researchers at Massachusetts General Hospital developed a novel cannula delivery system for effective compound administration during multiphoton microscopy, allowing for extended in vivo brain imaging.

Researchers at Tokyo University of Science have developed Chol-HDOs, which efficiently penetrate the brain, overcoming challenges associated with delivering gene-targeting drugs to brain tissue.

Researchers have developed a treatment for Parkinson’s disease that involves creating nerve cells from embryonic stem cells and transplanting them into patients. Early results show the treatment is safe and may improve Parkinson’s symptoms.

Weight loss drugs, including GLP-1RAs, might offer new ways to reduce dementia risk. Discover the latest research and what it means for Alzheimer's treatment.

A study identifies beta-synuclein in blood as a potential early biomarker for Alzheimer’s disease. This protein’s levels rise 11 years before cognitive symptoms, offering promise for early diagnosis and improved treatment outcomes.

A new study reveals that individuals aged 45 and older who had an emergency department visit or hospitalization due to cannabis were at 23% and 72% greater risk of developing dementia within five years compared to other groups.