Neurodegeneration – News and Features

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11 Genes Linked to Brain’s Response to PFAS Chemicals
Researchers have uncovered 11 genes that may hold the key to understanding how our brains respond to PFAS chemicals.

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Membrane Anchors Stabilize Proteins in Prion Diseases
Researchers at Ruhr University Bochum discovered that a lipid anchor on nerve cell membranes stabilizes prion protein folding, preventing harmful aggregation linked to prion diseases.

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Brain Circuits Behind Maternal Care Offer Clues to Autism
Cold Spring Harbor Laboratory researchers revealed how the brain integrates smell and sound signals to guide maternal behaviors in mice. The study identified key roles for the basal amygdala and auditory cortex in sensory processing.

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Microglia “Spit” Enzymes at Large Alzheimer’s Plaques
Microglia can partially break down amyloid plaques by "spitting" a digestive enzyme at them, a new study has found.

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“Good” Cholesterol Plays a Role in Gray Matter Maintenance
UT Southwestern researchers discovered that small HDL particles are linked to greater gray matter volume and better cognitive function in middle-aged adults. The study highlights the role of HDL function, not just concentration, in brain health.

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Mediterranean Diet May Boost Memory by Altering Gut Bacteria
A new study suggests that altered gut bacteria may cause the brain-boosting benefits of the Mediterranean diet.

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Ketamine Restores Movement Control in Parkinson’s Patients
University of Arizona researchers uncovered how levodopa-induced dyskinesia disrupts motor cortex function in Parkinson’s patients. Exploring ketamine as a treatment, they found it promotes neuroplasticity and restores control over movement.

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Herpes Virus Linked to Alzheimer's Pathology
A study from the University of Pittsburgh reveals a surprising link between Alzheimer’s disease and HSV-1. The research shows tau protein may initially protect the brain from the virus but later contribute to damage.

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Advanced Epigenetic Clocks Reveal Cellular Aging Insights
A new method using cell-type-specific epigenetic clocks measures biological aging in neurons, glia and liver cells, revealing rapid aging in Alzheimer's and liver diseases. This tool improves understanding of aging-related diseases.

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Not All Cell Types in the Brain Age in the Same Way
Scientists have identified specific cell types in mice brains that change drastically as they age, which could pave the way for future therapies to slow brain aging.
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