Next-Generation Sequencing – News and Features

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Blood Test for HPV Cancer Achieves 99% Sensitivity
Mass General Brigham researchers developed HPV-DeepSeek, a liquid biopsy blood test achieving 99% sensitivity for early detection of HPV-associated head and neck cancers. The test offers a highly accurate screening method.

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Asian Wild Spinach Could Hold Key to Pathogen Resistance
The researchers identified several varieties of wild spinach associated with resistance to Fusarium wilt.

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Genetic Mapping Unveils Mysteries of Ocean Worm Reproduction
The University of Göttingen’s research has mapped the genetic activity of the branching marine worm Ramisyllis kingghidorahi. The study highlights how this unique creature controls reproduction across its branches and stolons.

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Infant Immune System Reacts Uniquely to COVID-19
Scientists at St. Jude Children’s Research Hospital and their colleagues studied immune responses to mild, moderate and severe COVID-19 in infants.

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Genetic Mutation Rates in Kids Tied to Parents’ Smoking Habits
A study of 10,000 parent-child trios reveals that children’s new genetic mutations vary slightly by parental ancestry and smoking history. Researchers found African ancestry and parental smoking modestly increase mutation rates.

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How the Malaria Parasite Avoids Immune Detection
Researchers at Weill Cornell Medicine have discovered how a parasite that causes malaria when transmitted through a mosquito bite can hide from the body’s immune system, sometimes for years.

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AI Predicts Bacterial Resistance to Cleaning Agents
Researchers have developed a method that, with the help of AI and DNA decoding, can predict how well disease-causing bacteria tolerate disinfectants. This may become a valuable weapon in the fight against harmful bacteria in the food industry.

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"Rogue" Immune Cells Explain Why a Gluten-Free Diet Fails in Some Celiac Patients
Scientists have identified mutated immune cell clones that drive intestinal inflammation in people with celiac disease, explaining why a gluten-free diet sometimes fails.

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Why a Mutation in Ginger Cats Might Explain Both Color (and Chaos)
A Stanford-led study has identified a mutation on the X chromosome that causes orange fur in cats. The mutation switches on the normally silent Arhgap36 gene in pigment cells, blocking black/brown pigment production.

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AI and Genetics Data Help Farmers Grow Corn With Less Fertilizer
AI analysis has identified genes that affect nitrogen use efficiency in corn, which could mean cost savings and better crops for farmers.
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