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Screening Strategies in Drug Discovery – News and Features

A red and blue capsule broken in two, revealing drug molecules.

Using AI To Accelerate Novel Drug Design

Researchers have developed a platform that combines automated experiments with AI to predict how chemicals will react with one another, which could accelerate the design process for new drugs.
A lab worker.

New Material Gulps Down Hydrogen, Spits It Out To Protect Fusion Reactor Walls

University of Wisconsin–Madison engineers have used a spray coating technology to produce a new workhorse material that can withstand the harsh conditions inside a fusion reactor.
Pipette tips transferring liquid to a multi-well plate.

Revolutionizing High-Throughput Drug Screening With AI and Organoids

Thanks to the rise of AI, HTS for drug discovery is taking a more intelligent, computational approach, with tools that allow scientists to pinpoint the most promising drug candidates faster. Explore how this evolution will be further enhanced by a shift from 2D to 3D biological models such as organoids.
Two microfluidic chips

A Guide to Organ-on-a-Chip

By replicating the microenvironment of human organs within microscale devices, OOAC technology has emerged as a powerful tool for understanding human physiology and disease mechanisms with unparalleled precision.
Representation of cells.
Industry Insight

Maximizing Cell Line Productivity and Efficiency

In this interview, Dr. Tabitha Bullock tells us about some of the key considerations in cell line development and how advances in technology are improving the efficiency and productivity of cell lines.
Oil droplets.

High-Throughput Mass Spectrometry Platform Enables In Situ Screening of Fatty Acid-Producing Strains

A high-throughput mass spectrometry platform has enabled the in situ screening of fatty acids, showing it to be an efficient tool for fatty acid biomanufacturing.
Computer-generated image of a cancer cell.

Nutrient in Beef and Dairy May Improve Immune Cell Responses to Cancer

A fatty acid found in meat and dairy has been found to increase cancer-fighting T-cell activity according to a new study, suggesting trans-vaccenic acid has the potential to be used as a nutritional supplement to complement cancer therapies.
Small molecule closeup
Industry Insight

Confident Metabolite Identification for Meaningful Results in Multiomics Analyses

In this interview, Technology Networks spoke to Heiko Neuweger, director of Bioinformatics Life Science Mass Spectrometry Software R&D at Bruker, to learn about the importance of target compound annotation and identification, the advantages of integrating collision cross section (CCS) information into workflows and the benefits of CCS-Predict Pro.
A strand of silver-gray colored DNA.

Genome’s “Master” Regulator Could Be Used To Enhance T-Cell Therapy

A single master regulator of the genome can be used to reprogram a network of thousands of genes in T cells and greatly enhance cancer cell killing.
Droplets of liquid falling from pipette tips into a multiwell plate.

Extracting Meaningful Data With High-Throughput Drug Discovery Approaches

This article focuses on the use of high-throughput screening approaches in drug discovery and discusses the latest developments in this area.