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Single-Cell Analysis – News and Features

Abstract digital artwork of a human figure dissolving into colorful particles and lines, symbolizing the concept of spatial transcriptomics and biological data visualization.
Article

Spatial Transcriptomics Is in a Phase of Rapid Growth

Technology Networks spoke to the most productive researcher in spatial transcriptomics, Professor Joakim Lundeberg, about the field’s rapid growth.
A woman lying on a couch holding her stomach in discomfort, symbolizing symptoms of PCOS (Polycystic Ovary Syndrome) such as pain and fatigue.
News

Metformin Restores Endometrial Health in PCOS

A new study reveals that metformin, beyond managing blood sugar, restores endometrial health in women with PCOS. The drug improves cell adhesion and gene expression in the uterine lining, potentially reducing miscarriage risk and improving fertility.
A needle drawing liquid from a vial of vaccine.
News

New Insights Into B Cell Mutations Could Improve Vaccine Strategies

Successful high-affinity B cells can proliferate under special conditions that reduce the risk of mutation. Capturing this mechanism in the lab may lead to more efficient vaccine strategies in the clinic.
Co-cultures consisting of neurons that form nerve fibers (pink) and oligodendrocytes that coat these nerve fibers with myelin (white). The cell nuclei are stained blue.
News

Inflammation, Not Just Plaques, May Drive Alzheimer's Progression

A new study reveals that IL-12, an inflammatory molecule, accelerates Alzheimer’s disease by damaging brain cells and preventing plaque clearance. Blocking IL-12 in mice halted disease-related changes, suggesting a potential new therapy.
Multicolored cells in an organoid.
News

Pig Retinal Organoids Could Advance Cell Therapy for Eye Disease

Researchers have developed pig retinal organoids to understand how stem cell-derived photoreceptor cells work as a therapeutic.
3D rendered microscopic image of T cells.
News

Cancer Immunotherapy Enhanced by Rewiring T-Cell Metabolism

Researchers from the VIB-KU Leuven Center for Cancer Biology, in collaboration with other scientists, have discovered a way to enhance the immune system's ability to fight cancer by reprogramming T-cell metabolism.
Immune cells and antibodies.
News

How Trypanosomes Alter Their Antigen Expression To Evade the Immune System

Antigenic variation is a key mechanism by which pathogens evade the immune system. New research has shown how trypanosomes change their antigen expression.
A man sleeps on a bed with striped bed linen.
News

How Circadian Rhythms Affect Muscle Repair

Our circadian clock doesn't just dictate when we sleep – it also determines how quickly our muscles heal, with muscle injuries healing faster when they occur during natural waking hours.
An overweight person with a sandwich.
News

Researchers Uncover Cause of Leptin Resistance – And How To Reverse It

90% of people with obesity have leptin resistance – new research has found a mechanism involved and a way to reverse it using a well-known drug.
A cluster of cancer cells.
News

Reprogramming Aggressive Cancer Cells Into Harmless Ones

UCLA scientists have identified a potential new strategy for treating glioblastoma, the deadliest form of brain cancer, by reprogramming aggressive cancer cells into harmless ones.
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