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Single-Cell Analysis – News and Features

Portrait of Dr. Elizabeth Neumann featured in a “Women in Life Sciences” spotlight with scientific illustrations.
Article

Persistence and Progress: A Scientist’s Path Through Adversity and Innovation

In this interview, Dr. Elizabeth Neumann discusses her journey into science, her research utilizing single-cell analysis and her commitment to mentorship and advocacy.
Interacting with T cells (yellow) in the central nervous system of SPG15-deficient mice. Cell nuclei are shown in grey.
News

Brain Inflammation May Be the Hidden Trigger Behind Spastic Paraplegia

In the early stages of spastic paraplegia, the brain appears to play a major role by over-activating the immune system, as shown by a recent study. These findings could also be relevant for Alzheimer's disease and other neurodegenerative conditions.
A tape measure coils across the image, illustrating weight gain.
News

Stem Cells Enhance Production of Abdominal Fat as We Age

New research has uncovered the cellular culprit behind age-related abdominal fat, revealing why waistlines expand in middle age and offering new targets for therapies.
Images from the research paper show an increase in neurogenesis (as indicated by two markers: Ki67 and EdU) in mice exposed to 40Hz stimulation compared to those exposed only to ambient light and sound. Yellow arrows highlight instances of the markers.
News

40Hz Sensory Stimulation Improves Cognition in Down Syndrome Mice

MIT researchers demonstrated that 40Hz sensory stimulation improves cognition, hippocampal activity and neurogenesis in Down syndrome mice. The study, using synchronized light and sound, revealed increased gene expression linked to synapse formation
Purple cancer cells swirl around normal cells.
News

Cell Atlas Maps Molecular Changes in Neuroblastoma

A longitudinal atlas of neuroblastoma, a common and deadly childhood cancer, could uncover the precise molecular mechanisms underlying why and how certain treatments eventually become ineffective.
Close-up of a curious guinea pig looking up, with a grassy background.
News

Guinea Pigs Used to Study Human Embryo Development and Infertility

A study reveals that guinea pigs can serve as a robust model for understanding human pre-implantation development. Their similarities to humans in early embryogenesis open new avenues for infertility research and reproductive technologies.
Gold, star shapes representing neurons.
News

Newly Identified Neural Stem Cells Could Transform Parkinson's Treatment

The detection of peripheral neural stem cells could transform the treatment of Parkinson's disease and spinal cord injuries.
A crowd of people, standing closely together and facing the same direction.
News

World's First Immune Cell Atlas From Diverse Asian Populations Empowers Precision Medicine

Researchers from Singapore, South Korea, Japan, Thailand and India have assembled the world's first Asian Immune Diversity Atlas – a multi-national survey of human blood at single-cell resolution.
Digitally rendered neurons with glowing synapses, illustrating brain activity related to Tourette’s syndrome.
News

Brain Study Reveals Key Cellular Changes Behind Tourette Syndrome

A new study provides insights into Tourette syndrome by analyzing individual brain cells. Researchers found key changes, including a loss of interneurons, metabolic stress in medium spiny neurons, and increased inflammatory activity in microglia.
Microscopic view of an early-stage embryo during embryonic development under lab conditions.
News

Mimicking Embryonic Development Enhances Organoid Growth

A recent study found that placenta-derived IL1α under hypoxic conditions, can greatly increase growth of human stem cell-derived liver organoids. This method offers a promising route to improve organoid models and regenerative medicine.
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