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Single-Cell Analysis – News and Features

Double helix structure of DNA.
News

Mutated Histone-Modifying Gene Leads to Autism in Mice

Now, researchers from Japan have developed an animal model and elucidated the mechanism by which mutation in genes involved in chromatin modification causes autism. They have also discovered a drug that can be used in the treatment of autism.
A magnifying glass over human ovaries with five other human organs pictured around it.
News

New “Atlas” of the Human Ovary a Step Towards Artificial Ovaries

A new “atlas” of the human ovary provides insights that could lead to treatments restoring ovarian hormone production and the ability to have biologically related children, according to University of Michigan engineers.
A group of scientists discussing.
Industry Insight

Breaking Barriers: The Challenges Faced by 6 Biotech Start-Ups in 2024

At the European Laboratory Research and Innovation Group’s (ELRIG) Research and Innovation 2024 event, we asked a selection of start-up companies in the biotech space the same question: what are the key challenges you currently face?
A computer chip that looks like a human brain.
News

AI Tool Maps Soft Tissue Sarcomas

Soft tissue sarcomas are rare and difficult to treat. Machine-learning tools designed at Stanford Medicine uncover distinct cellular communities that correlate with prognosis, immunotherapy success.
A woman holding her stomach in pain.
News

Endometriosis: What’s the Latest Research?

Endometriosis represents a multifaceted challenge affecting millions of individuals globally. Recent studies have massively advanced our understanding of how the condition affects individuals and is helping to improve the lives of those affected.
A row of pipettes filled with red liquid
Article

High-Throughput Screening: Advances, Applications and Combined Approaches

In this article, we highlight various high-throughput screening strategies being used to interrogate large libraries of compounds and hear from researchers working to further streamline specific approaches to increase speed and improve quality and accuracy.
Cell therapy.
News

Study Paves the Way for “Off-the-Shelf” Cervical Cancer Cell Therapy

Researchers from Japan demonstrate that gene editing can enhance the effectiveness of rejuvenated cytotoxic T lymphocytes for targeted immunotherapy.
Red cancer cells adhered to a grey surface.
Article

Tumor Heterogeneity: Navigating the Next Frontier in Cancer Research

Some types of cancer are still extremely challenging to successfully treat. Once the disease has spread, it is very hard to cure. This article will explore the various types of tumor heterogeneity, how heterogeneity can impact treatment resistance and its influence on precision medicine.
Human cells.
Article

The Need To Scale Single-Cell Functional Studies

Kathrin Herbst reviews the pros and cons of various single-cell technologies and discusses the need to move to functional readouts in the future.
Cancer cells.
News

New Study Reveals Targetable Mechanism in Pancreatic Cancer Metastasis

A research paper published in Nature Cancer details new insights into the role of efferocytosis – the burying of dead cells – in pancreatic cancer that spreads to the liver.
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