Single-Cell Analysis – News and Features

90% of people with obesity have leptin resistance – new research has found a mechanism involved and a way to reverse it using a well-known drug.

UCLA scientists have identified a potential new strategy for treating glioblastoma, the deadliest form of brain cancer, by reprogramming aggressive cancer cells into harmless ones.

While controlling swelling caused by brain cancer is important, a new study shows that a commonly prescribed anti-swelling drug suppresses the immune system for weeks after dosage, inhibiting the body’s ability to fight the cancer.

Researchers find four coordinated gene expression programs in immune cells from glioma tumors, including two that could lead to immunotherapy resistance.

A new study from researchers at the University of Leipzig Medical Center and collaborators, has discovered a rare but serious side effect of CAR T-cell therapy in a 63-year-old patient.

New research brings scientists one step closer to understanding Rett Syndrome, a rare genetic disease that affects 1 in 10,000 newborn girls.

Two therapeutic "cocktails" could stop immune cells from overreacting to allergens, providing long-lasting asthma relief.

University of Michigan researchers developed a sponge-like implant that tracks early immune activity in MS-like disease. Using insights from the implant, they designed nanoparticles that halted or reduced symptoms in mice.

Researchers have discovered that chronic intermittent fasting disrupted the development of insulin-producing beta cells in young mice. The findings raise concerns about potential risks for humans, especially teenagers.

New studies show that bird and mammal brains evolved separately, with distinct genetic programs and developmental mechanisms. Researchers found that these species developed similar functions through different evolutionary paths.