Single-Cell Analysis – News and Features

New tools are enabling researchers to explore individual cells with unprecedented clarity, allowing RNA and protein expression levels to be simultaneously analyzed. In this blog, Brian Lilhanand, Global Platform Leader, Single Cell Multiomics, at BD, discusses how BD’s new AbSeq Assay can provide this targeted profiling and benefit immunology researchers.

With more and more applications of the microfluidics industry becoming apparent, giving scientists the tools they need has never been more important. This article highlights major industries that benefit from microfluidic technology, and provides insights into how demands for microfluidic components are changing.

Researchers have shown that triple negative breast tumours - which are the most aggressive and have the fewest treatment options - might one day be treated with a drug that cuts the 'phone lines' between normal cells and tumour cells.

A new study has identified where the mutation causing glioblastoma starts. According to the study, neural stem cells away from the tumor mass are the cells of origin that contain mutation drivers for glioblastoma.

A previously unknown airway cell type may be the key to understanding cystic fibrosis.

An LMU team has improved both the sensitivity and efficiency of a popular method for single-cell RNA sequencing, which yields a molecular fingerprint for individual cells based on their patterns of gene activity.

40 subtypes of retinal ganglion cells classified, raising questions about what constitutes a cell type or subtype

The complexity of the human brain presents scientists with immense challenges as they try to find new treatments for a host of diseases and conditions. But the advent of a new technology known as single-cell RNA sequencing is opening a window into how the brain works.

In the first of a two-part blog series, we discuss the advantages of a modular approach to bioinformatics with Dr. Misha Kapushesky, CEO and Founder of Genestack. Perviously a Team Leader at the European Bioinformatics Institute, we also learn about Misha's move from Institute to industry.

Resarchers analyzed 1.3 million cells and unraveled an unprecedented heterogeneity in rare cell populations during mouse brain development.