The Immune System – News and Features

A fungal infection has been shown to trigger a fruit fly’s immune system to destroy brain cells leading to signs of neurodegeneration, a new study has found.

Researchers have developed a new gene switch that can be activated using a commercially available nitroglycerine patch applied to the skin. One day, researchers want to use switches of this kind to trigger cell therapies for various diseases.

UConn researchers have identified a small molecule that disrupts PRRSV, a virus costing the swine industry billions annually. The molecule blocks the NendoU protein, reducing viral replication 1,000-fold.

The world’s largest collection of digital microbes - nearly a quarter million computer models - could help revolutionize our understanding of the human microbiome and its impact on health.

New research explores the cellular fight for iron during COVID-19 infection, unraveling the body's defense mechanisms and the viruses means of attack.

New findings outline the differences in the gut microbiome of infants with cystic fibrosis, compared to healthy infants, and how these changes may affect health.

In a new study, researchers have found that changes in two parts of the genome work together to influence alopecia risk.

Researchers reveal how MAGE-4 and PTEN loss drive cancer growth, suppress immunity and point to new therapeutic strategies to fight tumors.

Researchers at the University of Chicago Medicine identified vitamin E succinate (VES) as an effective agent in suppressing tumor growth by promoting FTO degradation. This enhances T-cell cytotoxicity and improves response to immunotherapy.

A study from ISGlobal found that second-hand smoke exposure in childhood causes epigenetic changes in 11 DNA regions, potentially affecting disease risk in adulthood. These changes highlight the need for stronger public health measures.