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The Immune System – News and Features

A child looking through a toy.

Genetic Risk Factors for Autism Linked to Distinct Cellular Changes

A new single-cell study from the PsychENCODE initiative links genetic risk factors to cellular changes in ASD brains. The research, published in Science, provides insight on the potential causal mechanisms behind ASD.
A 3D model of a human heart.

Previously Unknown Changes in the Right Atrium Linked to Heart Disease Progression Uncovered

The study reveals how various forms of heart disease drive changes in the right atrial tissue and pericardial fluid, potentially contributing to the disease progression.
B cells segregating specific antibodies to mark and subsequently destroy a virus

Metabolic Inhibition Offers a New Approach To Combat Epstein-Barr Virus

Inhibiting a specific metabolic pathway in EBV-infected B cells can diminish infection and reduce the risk of downstream disease. A class of “failed” inhibitor drugs may now receive a second chance in applications aimed at dampening EBV infection.
A fish, camoflaged on the sea bed.

Sexual Parasitism Helped Anglerfish Conquer the Deep Sea

Sexual parasitism works in synergy with other traits associated with anglerfish to influence their diversification, enabling them to survive in the deep oceans.
A trowel spills compost over a worktop. A plant pot sits next to it.

Gardeners Benefit From Microbial Exposure That Boosts the Immune System

A one-month indoor gardening period increased the bacterial diversity of the skin and was associated with higher levels of anti-inflammatory molecules in the blood.
A SARS-CoV-2 lateral flow assay on top of a mask.

The COVID-19 Pandemic Caused a Surge in a Rare Health Condition

A rare condition surged among previously unaffected groups of people during the COVID-19 pandemic, researchers report.
Chickens in the grass.

Experimental mRNA Vaccine Could Limit the Impact of Avian Flu Outbreaks

An experimental mRNA vaccine against avian influenza virus H5N1 is highly effective in preventing severe illness and death in preclinical models.
Dr. Sangeeta Goswami stands at a lab bench,

Pioneering Immuno-Oncology Through a Love of Science

This article profiles Dr. Sangeeta Goswami, a physician-scientist who is at the forefront of immunotherapy research and champions young doctors, especially women, eager to pursue similar paths.
Cancer cells

Helping Immune Cells Fight Cancer

In this article, we will explore the obstacles that reduce the efficacy of cell-based cancer immunotherapy and strategies to overcome them.
A girl sitting on a chair looking out a window.

PTSD and Depression Have Shared and Distinct Brain Molecular Dysregulations

McLean Hospital researchers uncovered both shared and distinct molecular changes across brain regions, genomic layers, cell types and blood in individuals with posttraumatic stress disorder (PTSD) and major depressive disorder (MDD).