Therapeutic Antibodies – News and Features

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells.

Sneaking by cancer’s defenses, by disguising tumor-fighting antibodies inside the molecules cancer uses to nourish tumor growth, is the basis of a novel therapy from Yale Cancer Center researchers at the Yale School of Medicine (YSM).

Early findings from a small clinical trial provide evidence that a new cellular immunotherapy approach may effectively treat metastatic solid tumors.

In this article, one of the leading quality control strategies being implemented by pharmaceutical manufacturers is discussed.

Researchers at LJI and Columbia University uncover exactly how a neutralizing antibody blocks measles virus infection

In this article, we explore how mass spectrometry imaging technology is evolving into a high-resolution spatial biology toolset to transform drug discovery and development.

Researchers develop fully human antibodies that can neutralize the alpha-latrotoxin of the European black widow, potentially reducing the need for antibodies derived from horses to treat disease caused by spider bites.

A combination of oncolytic virotherapy and an immune checkpoint inhibitor has shown promise for unresponsive bladder cancer.

We spoke with Dr. Christian Dillon to learn more about degradation-based therapies, the challenges associated with their discovery and how innovative solutions are helping to realize the potential of this promising class of therapeutics.

A consortium of scientists have developed a promising new human monoclonal antibody that appears a step closer to a universal antibody cocktail that works against all strains of SARS-CoV-2.