Therapeutic Antibodies – News and Features

Explore types of therapeutic proteins, design strategies and the production methods used in treating cancer, autoimmune diseases and more.

A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis.

Understanding what is happening inside the “black box” of large protein models could help researchers choose better models for a particular task, helping to streamline the process of identifying new drugs or vaccine targets.

A protective polymer coating is helping scientists to pack proteins into a liquid at high concentrations, enabling alternatives to lengthy intravenous infusions.

An antibody originally designed to combat dengue virus may also inhibit the spread of Zika virus in vulnerable areas of the body, a study in preclinical models has found.

In initial testing in lab mice, a monoclonal antibody proved versatile and showed “transformative potential for combatting life-threatening inflammatory diseases,” researchers report.

A research team has uncovered how glycan modifications dynamically regulate the structure and function of human immunoglobulin G antibodies. The findings provide a new framework for designing next-generation therapeutic antibodies.

A two-drug combination for treating advanced kidney cancer had sustained and durable clinical benefit in more than five years of follow-up.

Discover essential antibody purification methods, from affinity chromatography to ion exchange chromatography, for research and therapeutic applications.

This article explores how innovative screening methods and AI are advancing therapeutic antibody discovery by improving throughput, reducing bias and enabling deeper insights.