Therapeutic Antibodies – News and Features
News
Immunotherapy After Kidney Cancer Surgery Improves Overall Survival
For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.
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Microbial Monitoring for Biopharma Manufacturing
Contamination is a significant issue for bioprocessing as it results in loss of time, money and effort. This article will explore the pivotal role of microbial monitoring in upholding product safety and quality standards within the biopharmaceutical industry.
News
Designing a Vaccine To Block “Zombie Drug” Xylazine
Scripps Research chemical biologists have developed a vaccine to block the effects of xylazine’s toxicity. The vaccine works by training the immune system to attack the drug, which is described in a new paper published in Chemical Communications.
News
Immunotherapy Clears Amyloid Plaques in Alzheimer’s Mouse Model
Researchers have found a different and promising way to remove the noxious amyloid plaques in Alzheimer's disease: by directly mobilizing immune cells to consume them.
News
Antibody Target Identified Against Crimean Congo Hemorrhagic Fever Virus
CCHFV poses a threat to U.S. military personnel and hospital staff as well as residents of a growing number of countries, says UC Riverside biomedical scientist.
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Researchers Identify Epstein-Barr Virus’ Weak Points
Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.
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Breast Cancer Drug's Efficacy Can Be Restored After Resistance
Researchers have shown that targeting a protein called TACC3 (transforming acidic coiled-coil containing protein 3) can restore the effectiveness of the breast cancer drug T-DM1 if the cancer cells have developed resistance.
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Cell-to-Cell Communication in Cancer
We typically think of a cancerous tumor as a bunch of abnormal cells gone rogue, but the situation is more complicated. This article will explore cell-to-cell communication’s role in cancer development, its influence on metastasis and how research is expanding our knowledge of the disease.
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Breakthrough for Breast Cancer Bone Metastases
A promising new immunological pathway that could be used to treat breast cancer that has metastasized to bone has been identified.
News
Previously Unknown Immune Evasion Regulator in Tumors Identified
Northwestern Medicine investigators have identified a previously unknown regulator of tumor immune evasion, which may help improve the efficacy of current and future anti-tumor immunotherapies.
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