Therapeutic Antibodies – News and Features

CCHFV poses a threat to U.S. military personnel and hospital staff as well as residents of a growing number of countries, says UC Riverside biomedical scientist.

Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.

Researchers have shown that targeting a protein called TACC3 (transforming acidic coiled-coil containing protein 3) can restore the effectiveness of the breast cancer drug T-DM1 if the cancer cells have developed resistance.

We typically think of a cancerous tumor as a bunch of abnormal cells gone rogue, but the situation is more complicated. This article will explore cell-to-cell communication’s role in cancer development, its influence on metastasis and how research is expanding our knowledge of the disease.

A promising new immunological pathway that could be used to treat breast cancer that has metastasized to bone has been identified.

Northwestern Medicine investigators have identified a previously unknown regulator of tumor immune evasion, which may help improve the efficacy of current and future anti-tumor immunotherapies.

New research has identified three subgroups of triple-negative breast cancer patients, based on how the tumor responds to therapy. This could enable clinicians to employ aggressive treatments only when needed.

Research shows that some lung cancer cells retain a “memory” of the healthy cell where they came from — one that might be exploited to make an emerging type of lung cancer treatment called KRAS inhibition more effective.

A diverse array of biological medicines are now used to prevent and treat a wide range of illnesses. This article will discuss the development of cell lines in biopharma and will touch on key considerations, such as future manufacturability.

Andrew Schulman explores why we need allogeneic therapies, the importance of collaboration to keep the momentum, and challenges and predictions for the future.