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Therapeutic Delivery – News and Features

A digital illustration of a cell.

“Message in a Bottle” Cancer Therapy Shows Promise in Mice

Researchers have used small membrane bubbles – which our cells use to communicate – to deliver targeted cancer treatments to tumors in mouse models, demonstrating reduced tumor growth and extended survival in one model.
A 3D model of a human heart.

Adhesive Coatings Can Prevent Scarring Around Medical Implants

MIT engineers found a way to eliminate the buildup of scar tissue around implantable devices, by coating them with a hydrogel adhesive. The material binds the device to tissue and prevents the immune system from attacking the device.
Cancer cells.

Mouse Study Explores Why Glioblastoma Treatment May Work Better in the Morning

Glioblastoma is an aggressive brain cancer that has no cure. A recent chart study of patients with glioblastoma found that taking chemotherapy in the morning was associated with a three- to six-month increase in median survival.
Two researchers at a whiteboard.

Physicists Propose Path to Faster, More Flexible Soft Robots

Physicists have revealed a microscopic phenomenon that could greatly improve the performance of soft devices, like flexible robots or microscopic capsules for drug delivery.
Double helix structure of DNA.

Designing Peptoids That Mimic Nature’s Helices

Nature is filled with extraordinarily precise molecular shapes that fit together like a hand in glove. Proteins, for example, can assemble into a wide variety of well-defined shapes that grant them their function.
An individual holding up a piece of hair that has come out of their head.

Microneedle Patch Offers Hope for Alopecia Areata Treatment

Researchers developed a potential new treatment for alopecia areata, an autoimmune disorder causing hair loss. The new microneedle patch delivers immune-regulating molecules that can teach T cells not to attack hair follicles, helping hair regrow.
The crystal structure of a lattice.

“Better Than Graphene” Material May Improve Implantable Technology

The atomically thin version of boron, borophene, has been made chiral to enable it to interact in unique ways with biological units.
A needle inserted into a vaccine vial.

Experimental mRNA Brain Cancer Vaccine Evaluated in Small Trial

A new mRNA vaccine has shown promise in activating the immune system against a highly lethal type of brain tumor, according to results from a first-in-human clinical trial of four adult patients with glioblastoma.
Someone holding out a test tube and a DNA double helix.

Electricity Could Make Cells More Receptive to Certain Gene Therapies

A team of researchers in electrical engineering at the University of Wisconsin–Madison has developed a stimulating method that could make the human body more receptive to certain gene therapies.
A 3D graphic representation of a spherical-shaped, measles virus particle.

Microarray Patches Safe and Effective for Vaccinating Children, Study Finds

The first study of the use of microarray patches to vaccinate children has shown that the method is safe and induces strong immune responses.