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Vaccine Design and Testing – News and Features

Cancer cells.
News

Vaccine Adjuvant Promotes Strong Anti-Tumor Immunity in Animal Models

They have discovered that a vaccine adjuvant – or “booster” – called C100 promotes potent anti-tumour immunity when it is injected directly into tumours in an animal model.
A clinician holds the results of a brain scan.
News

Developing a Personalized Vaccine Against Cancerous Brain Tumors

Pairing a personalized dendritic cell vaccine with an immune-boosting compound improves the immune response to malignant gliomas.
Synthetic biologists inserted genes from the soap bark tree and other organisms into yeast to create a biosynthetic pathway for building a complex molecule called QS-21, a powerful adjuvant used in vaccines. The chemical structure of QS-21 is in the background.
News

Vaccine Adjuvant Made in Yeast Could Lower Costs and Boost Availability

Many vaccines, including the Novavax COVID-19 vaccine, contain adjuvants that stimulate the immune system to mount a stronger defense. Producing one such adjuvant in yeast promises to make it less expensive and more widely available.
A person wearing a face covering receives a band-aid after a vaccine.
News

Third COVID-19 Vaccine Booster Improves Antibody Responses for Vulnerable Patients

A major clinical trial has found that an additional COVID-19 vaccine dose led to the majority of clinically extremely vulnerable people mounting defensive antibodies against the virus.
immunofluorescent staining shows a lymph node that has been significantly expanded in mice with the help of the biomaterial MPS-vaccine (on the right), next to a lymph node taken from non-treated control mice (on the left) at the same time post-vaccination.
News

Biomaterial Vaccine Enhances Lymph Node Expansion and Boosts Anti-Tumor Immunity

A biomaterial vaccine enhances and sustains lymph node expansion following vaccination, boosting anti-tumor immunity in an animal model.
A needle inserted into a vaccine vial.
News

Experimental mRNA Brain Cancer Vaccine Evaluated in Small Trial

A new mRNA vaccine has shown promise in activating the immune system against a highly lethal type of brain tumor, according to results from a first-in-human clinical trial of four adult patients with glioblastoma.
Epstein-Barr virus (EBV) stained with Hematoxylin and eosin (HE)
Article

Epstein-Barr Virus, Multiple Sclerosis and Cancer: Looking Back at 60 Years of Research

In this interview, Professor Lawrence Young discusses the current interest in Epstein-Barr virus (EBV) vaccines for combatting multiple sclerosis and his thoughts on the future direction of EBV research.
Ribosome translating mRNA into a polypeptide chain.
Industry Insight

Tuning the Therapeutic Properties of tRNAs To Treat Rare Diseases

Michelle C. Werner discusses how tRNAs could transform the drug development paradigm from gene-centric to gene-agnostic and accelerate new therapies for 30 million or more patients whose genetically driven disease can be classified under Stop Codon Disease.
A watercolor painting of viruses.
News

Novel Hydrogel Therapy Impedes Invading Pathogens

A novel hydrogel therapy could be a first line of defense against viruses and other biological threats.
An individual receiving a vaccination from a medical professional
News

Could a Novel RNA-Based Vaccine Strategy Stop Endless Boosters?

A novel vaccination strategy utilizing small interfering RNA molecules could protect infants from COVID-19 and flu with a single shot. The study suggests that the vaccine strategy could offer continued protection even if the virus mutates.
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