Vaccine Design and Testing – News and Features

Researchers have engineered two mycobacterial strains with built-in kill switches that trigger self-destruction after immune activation. These strains enhance the safety of high-dose intravenous BCG vaccines.

Researchers developed a cancer vaccine that uses tumor lysate to enhance immune recognition of solid tumors. The vaccine successfully targets melanoma, breast, lung and ovarian cancers in animal models.

A group of Berlin researchers in collaboration with international scientists have found differences in heart inflammation caused by COVID-19, anti-COVID-19 vaccination, and non-COVID-19 myocarditis.

Researchers developed Deep Nanometry, a high-speed AI-powered technique that detects rare nanoparticles such as extracellular vesicles (EVs) linked to early-stage cancer. This deep learning-based noise removal method improves sensitivity.

Researchers have, for the first time, introduced genetic material into plants via their roots, opening a potential pathway for rapid crop improvement.

Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially be more susceptible to macrophage-based therapies.

In a step toward combatting Salmonella infections, researchers have identified a potential vaccine.

New research challenges previous assumptions about RNA transport, finding that RNA can carry instructions across generations.

A prophylactic antibody-based immune therapy has been shown to protect monkeys against severe bird flu caused by H1N1.

A new reverse mutational scanning approach can detect viral mutations responsible for immune evasion in new virus variants.