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Vaccine Design and Testing – News and Features

Mycobacterium tuberculosis bacteria, the pathogen responsible for causing the disease tuberculosis (TB).
News

Controlled Kill Switches Improve TB Vaccine Safety

Researchers have engineered two mycobacterial strains with built-in kill switches that trigger self-destruction after immune activation. These strains enhance the safety of high-dose intravenous BCG vaccines.
Cancer cells.
News

Cancer Vaccine Improves Antigen Visibility in Tumors

Researchers developed a cancer vaccine that uses tumor lysate to enhance immune recognition of solid tumors. The vaccine successfully targets melanoma, breast, lung and ovarian cancers in animal models.
Anatomical model of human heart.
News

Myocarditis Differs Depending On the Cause

A group of Berlin researchers in collaboration with international scientists have found differences in heart inflammation caused by COVID-19, anti-COVID-19 vaccination, and non-COVID-19 myocarditis.
A magnifying glass.
News

Machine Learning-Powered “Deep Nanometry” Helps Reveal Disease-Related Nanoparticles

Researchers developed Deep Nanometry, a high-speed AI-powered technique that detects rare nanoparticles such as extracellular vesicles (EVs) linked to early-stage cancer. This deep learning-based noise removal method improves sensitivity.
The tip of a plant's root, with bright green mRNA present.
News

Genetic Material Delivered Into Plant Roots for First Time

Researchers have, for the first time, introduced genetic material into plants via their roots, opening a potential pathway for rapid crop improvement.
Holographic image of human body with pancreas shown in red.
News

Immune Mapping of Pancreatic Cancer Offers Insights for Precision-Targeted Treatment

Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially be more susceptible to macrophage-based therapies.
Four rod-shaped Salmonella bacteria with long tails.
News

Vaccine Induces Antibodies in Mice Exposed to Wastewater Salmonella

In a step toward combatting Salmonella infections, researchers have identified a potential vaccine.
A strand of RNA coils across the screen.
News

How RNA Molecules Carry Instructions Across Many Generations

New research challenges previous assumptions about RNA transport, finding that RNA can carry instructions across generations.
A pair of antibodies, with different domains shown in different colors.
News

Antibody Treatment Protects Monkeys Against Severe Bird Flu

A prophylactic antibody-based immune therapy has been shown to protect monkeys against severe bird flu caused by H1N1.
A SARS-CoV-2 virion, with different spike proteins on its surface visible.
News

Reverse Scanning Offers Faster Approach for Identifying New Virus Variants

A new reverse mutational scanning approach can detect viral mutations responsible for immune evasion in new virus variants.
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