Vaccine Design and Testing – News and Features

Discover how RNA therapeutics are reshaping medicine, offering new treatments for previously undruggable targets.

A study conducted by researchers at Hokkaido University has unveiled a novel class of zwitterionic phospholipids capable of significantly enhancing the functional delivery of mRNA.

Researchers at the University of Cologne have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the human body to better protect itself against potential future infections.

Successful high-affinity B cells can proliferate under special conditions that reduce the risk of mutation. Capturing this mechanism in the lab may lead to more efficient vaccine strategies in the clinic.

A National Institutes of Health (NIH)-sponsored clinical trial of a candidate vaccine to prevent Lassa fever has begun enrolling participants at the University of Maryland School of Medicine, Baltimore.

Researchers have discovered how antibodies help to protect against contagious bacterial infections caused by Strep A, including strep throat. The findings are contributing to efforts to accelerate the development of a Strep A vaccine.

A new technology from researchers at the California NanoSystems Institute at UCLA is aiming to turn the tables on tumors that migrate from the pancreas to the liver.

Cornell researchers have developed a new vaccine platform that could provide more robust, longer-lasting protection from COVID-19 and influenza and broader immunity to different flu strains.

Researchers have engineered two mycobacterial strains with built-in kill switches that trigger self-destruction after immune activation. These strains enhance the safety of high-dose intravenous BCG vaccines.

Researchers developed a cancer vaccine that uses tumor lysate to enhance immune recognition of solid tumors. The vaccine successfully targets melanoma, breast, lung and ovarian cancers in animal models.