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Vaccine Design and Testing – News and Features

A needle piercing a vaccine vial bottle.
News

Viral Protein Analysis Used To Design New Vaccines Against Respiratory Viruses

Scripps Research scientists engineered stable RSV and hMPV F proteins, overcoming instability challenges to design effective vaccines. This approach showed promising results in mice and could lead to a combination vaccine for both viruses.
Researchers in a laboratory discussing data on a tablet, representing innovation in UK biotech startups.
Industry Insight

A Glimpse Into the Technologies Behind Upcoming UK Biotech Start-Ups

The Discovery Spark program aims to help upcoming biotechnology and healthcare companies grow. In this article, we take a closer look at some of the innovative technologies of this year's Discovery Spark cohort.
Two images, one showing how immune organ-on-a-chips are grown, the other a close-up of immune cell development in an organoid.
News

Lab-Grown Model Reveals Weakened Immune Response in Cancer Patients

Tiny lab-grown models of human immune systems are helping researchers understand why cancer patients struggle to fight infections.
A clinician wearing white gloves fills a syringe with a vaccine.
News

RSV Vaccination Earlier in Pregnancy Could Provide Better Protection for Newborns

New research has indicated that the ideal time for pregnant people to get vaccinated against RSV is at 32 weeks pregnant, to best protect their newborns.
Antibodies.
News

AI Tool Identifies Better Antibody Therapies

Georgia Tech researchers created AF2Complex, a deep-learning tool that predicts antibody interactions with proteins, enhancing immunotherapy development. The model accurately identified effective antibodies against Covid-19.
A three-dimensional (3D), computer-generated image, of a group of Gram-positive, Streptococcus pneumoniae bacteria.
News

Study on Emerging Streptococcus Subspecies Sheds Light on Increased Rates of Human Infections

Researchers at Houston Methodist studied the emerging strain Streptococcus dysgalactiae subspecies equisimilis (SDSE) and its virulence. The team revealed significant insights into SDSE's genomic and transcriptomic features.
Vaccine vials.
News

Researchers Identify Gene Behind HIV Vaccine Ineffectiveness

A study found a gene in human cytomegalovirus (HCMV) that can block immune responses needed for an effective HIV vaccine. This discovery could improve future vaccine designs for HIV and other diseases.
A microscope image showing how mRNA (labelled in red) is transfected across a mouse brain.
News

Could In Utero mRNA Therapy Fix Faulty Genes Before Birth?

A new mouse study shows how a new tool can deliver genetic material to edit faulty genes in developing fetal brain cells.
A pregnant person holds their baby bump.
News

Maternal Antibodies Disrupt Infants' Responses to Malaria Vaccines

Maternal antibodies passed across the placenta can interfere with the response to the malaria vaccine, explaining its lower efficacy in infant under five months of age.
Vaccine vials on ice.
News

mRNA Vaccine Provides Hope for Preventing C. difficile Infections

Researchers developed an mRNA vaccine that protects against C. difficile infections. The vaccine induces a strong immune response, promotes bacterial clearance, and shows potential for broader applications.
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