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Latest Whitepapers

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Quantify and Characterize Host Cell Protein With Confidence

Download this whitepaper to learn more about how dilutional linearity enhances reliability, undetected HCP can be minimized as well as consistently low variation ensures reproducible data.
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A Guide to Recombinant Antibody Engineering

Download this whitepaper to learn more about antibody engineering design parameters, different options including humanization and fragments as well as the future of antibody engineering.
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The Evolution of Next-Generation Sequencing

Download this whitepaper to discover how third generation sequencing can identify disease-causing variants with complex genetic etiology, detect SARS-CoV-2 and provide novel genetic insights.
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Defeating COVID-19: Seroconversion Detection With ELISA

Assays, such as the enzyme-linked immunosorbent assay (ELISA), are being developed to detect the presence of anti-SARS-CoV-2 antibodies in patient sera. Download this article to discover an ELISA that is more sensitive than a lateral flow immunoassay.
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Using LC-MS for Next-Gen Biologics: A Focus on Antibody-Drug Conjugates and Conjugation Chemistry

Download this whitepaper to discover how LC-MS can deliver unmatched analyte specificity for antibody-drug conjugates with high-throughput analyses and is useful in product development.
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Best Practices for Vaccine Research

Vaccination is largely recognized as the most cost-effective way to fight human infectious diseases. Vaccines play a vital role in immunization strategies that have helped to eradicate dangerous pathogens, increase human life expectancy and reduce disabilities and suffering all around the world.
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Rapid Implementation of Novel Affinity Purification

The rapid and cost-effective production of conventional monoclonal antibodies (mAbs) for clinical trials has contributed toward their wide adoption. As the number of next-generation antibody-based candidates with modified or absent Fc domains increases, biomanufacturers face a need to establish alternative affinity purification technologies.
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Improving Aggregate Removal To Enhance Clinical Manufacturing of mAbs

Over the past two decades, monoclonal antibodies (mAbs) have been one of the most dominant segments of the biotherapeutics market. Ensuring mAbs’ safety and efficacy is vital but is made complicated by the fact that antibodies can have a tendency to aggregate during production, decreasing efficacy and increasing the risk of immunogenicity.
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Affinity Tags Head Toward the Vaccination Clinic

Protein purification can be a challenging process. Since proteins are expressed in biological systems such as cells, the protein must be purified from a complex mixture. Generic column-based purification procedures exploiting differences in protein size and charge, tend to give imperfect results.
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Immunologic Testing for COVID-19

Preventive measures, accurate disease diagnostics and effective contact tracing are still considered fundamental in efforts to combat the SARS-CoV-2 pandemic. Download this whitepaper to discover serological testing methods, antigen testing methods and the impact of COVID-19 variants and antibody cross reactivity.
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