Automated Epitope Binning in a Single Assay
In the development of therapeutic monoclonal antibodies (mAbs), it is crucial to select lead candidates with optimal biological and pharmaceutical properties.
Binding affinity is a significant factor to consider. However, relying solely on affinity can be problematic, as the highest affinity mAbs may not exhibit optimal activity. To ensure the best lead candidates, it is crucial to consider factors like specificity, selectivity and biological relevance.
Epitope binning studies streamline candidate screening by pooling similarly behaving mAbs for further investigation in the development process.
Download this whitepaper to learn more about:
- The value of classifying mAbs by their binding behavior and biological functions
- How to group mAbs based on similar epitope binding regions
- Versatile, high-throughput technology for quick and accurate epitope binning