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Signals Notebook: Finally More Time For Science

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PerkinElmer Signals Notebook allows you to achieve meaningful scientific breakthroughs – faster and smarter.

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Using Supercomputers to Predict Dispersal of Chemicals and Pollutants

Article

Motivated by a deadly chemical attack in Syria, researchers at the University of Texas at San Antonio are pursuing research that may help save lives during an airborne chemical attack. The team used the Stampede2 supercomputer and innovative computer simulation models to replicate the dispersion of the chemical gas released in the Syrian event, which may help improve evacuation speed during future attacks.

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Answer the challenges of CDS Data integrity - Sterling Pharma Solutions Ltd

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Data integrity continues to be a hot topic for the regulatory agencies in the pharmaceutical industry.

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How AI Can Speed Up High Content Screening Analysis

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High content screeening (HCS) has become a staple tool for scientists trying to find out how molecules alter our cells' biological systems. The huge volume of data that HCS produces is both its strength and weakness. As assays become more complex, companies like Genedata are turning to AI-based approaches to help streamline HCS analysis. I spoke to Genedata's Head of Science, Dr. Stephan Steigele, to find out more.

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AI-Capnograph Distinguishes Between Emphysema and Heart Failure
AI-Capnograph Distinguishes Between Emphysema and Heart Failure
News

By analyzing carbon dioxide in the breath, an algorithm could help determine how to treat patients.

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Machine-learning System Could Aid Critical Decisions in Sepsis Care
Machine-learning System Could Aid Critical Decisions in Sepsis Care
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This predictive model could guide clinicians in deciding when to give potentially life-saving drugs to patients being treated for sepsis in the emergency room.

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Casting a Neural Net over RNA-Seq Data
Casting a Neural Net over RNA-Seq Data
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Computer scientists at Carnegie Mellon University say neural networks and supervised machine learning techniques can efficiently characterize cells that have been studied using single cell RNA-sequencing (scRNA-seq). This finding could help researchers identify new cell subtypes and differentiate between healthy and diseased cells.

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Computer-Aided Material Design Program Summarizes Thousands of Articles in One Chart
Computer-Aided Material Design Program Summarizes Thousands of Articles in One Chart
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NIMS and the Toyota Technological Institute at Chicago have jointly developed a Computer-Aided Material Design (CAMaD) system that enables information from thousands of scientific and technical articles to be summarized in a single chart, rationalizing and expediting material design.

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The Key to Unlocking HPC's Value?
The Key to Unlocking HPC's Value?
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Large-scale supercomputing is essential to solving complex questions about our world. But storage platforms essential for these advanced computer systems have been stuck in a rigid framework that required users to either choose between customization of features or high availability. Now, researchers have found a way to give high-performance computing data systems the flexibility to thrive with a framework called BespoKV, perhaps helping to one day achieve the HPC goal of performing at the exascale, or 1 billion billion calculations per second.

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Crystal Structure Predictor Inspired by Nature
Crystal Structure Predictor Inspired by Nature
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Scientists found a way of improving the crystal structure prediction algorithms, making the discovery of new compounds many times faster.

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Artificial Intelligence, Real Solutions: How AI Can Accelerate Drug Discovery

Artificial Intelligence, Real Solutions: How AI Can Accelerate Drug Discovery

Article

The rate at which new drugs are discovered is in decline, and computer-aided drug design has not produced the radical change in the success of candidate drugs the pharma industry anticipated. Artificial intelligence (AI)-based approaches are the new hope for revolutionizing the drug discovery process. But are these, as computer-aided drug design was, an over-hyped time bomb waiting to be found out? Or is it truly a revolution on the cusp of realizing its promise?

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Care in the Community – How Biofilms Improve Bacterial Survival
Article

A single bacterial cell on its own is vulnerable to attack and like many living things they can benefit from safety in numbers. But bacteria take communal living to a whole new level, forming veritable civilizations - the bacterial biofilm.

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Antigenic Drift vs Antigenic Shift
Article

As part of the host-pathogen arms race, viruses are continually evolving to evade the host immune response, be it from previous infection or immunity acquired through vaccination. Here we take a look at the processes of antigenic drift and antigenic shift.

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Healthcare Interoperability Woes: Three Solutions that Create Optimism
Article

Healthcare interoperability remains an intractable problem; both healthcare providers and patients feel unease about limited access to medical data, which results in lower care quality and poor patient engagement. Although daunting, these challenges aren’t insurmountable. In this feature, we’ll explore what has been and what could be done to foster the creation of an interoperable infrastructure.

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