Application Notes

 
A Novel Lipid Screening Platform that Provides a Complete Solution for Lipidomics Research
Application Note

SCIEX

A novel lipidomics platform was developed that includes simplified sample preparation, automated methods, and streamlined data processing techniques that enable facile, quantitative lipid analysis.

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Novel Chemical Standards Kits Enable Facile Lipid Quantitation
Application Note

SCIEX

The Lipidyzer platform provides more accurate lipid analysis with less quantitative bias.

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Global Mining Leader Implements LIMS to Support ISO 17025
Application Note

STARLIMS

Aspiring to satisfy the criteria for laboratory accreditation, Anglo American Research Labs searched for an ISO 17025 “ready” LIMS. STARLIMS aided in automating the lab to conform to ISO 17025 standards.

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The ROI of LIMS Standardization
Application Note

STARLIMS

Seeking a replacement for their internally developed LIMS, ChevronTexaco selected STARLIMS to standardize five domestic US refinery plants. The system is presently in production concurrently at all five sites, with 2,500 users.

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Replacing a Legacy LIMS at the Pacific Environmental Science Centre
Application Note

STARLIMS

The Pacific Environmental Science Centre (PESC) had been using a LIMS developed in the 1970s but, with multi-functionality required, covering 105 applications, and with 12 functional areas of the laboratory and around 500,000 tests conducted per year, the system was becoming increasingly more difficult and time-consuming to maintain.

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Minimizing Compliance Risk at Regulated Nutrient Manufacturer
Application Note

STARLIMS

Today’s laboratories are struggling to find ways to effectively solve their two most important issues: addressing regulatory compliance, including 21 CFR Part 11, and improving inefficient processes. Fortitech Inc.’s burgeoning task of managing and documenting ingredient blend quality procedures, invoked an initiative to fully automate lab operations.

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Qualitative and Quantitative Characterization of the Metabolome, Lipidome, and Proteome of Human Hepatocytes Stably Transfected with Cytochrome P450 2E1 Using Data Independent LC/MS
Application Note

Washington University School of Medicine

Drug toxicity is a major reason for the failure of candidate pharmaceuticals during their development. Therefore, it is important to realize the potential for toxicity in a timely fashion. A label-free multi-omics approach has been applied for the analysis of the transfected human hepatocyte cells by implementing LC/HDMSE, providing both qualitative and quantitative information within a single experiment.

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TransOmics Informatics Powered by Nonlinear Dynamics
Application Note

Washington University School of Medicine

This application note introduces the workflow of TransOmics Informatics Software that has been specifically developed for the larger scale analysis of ion mobility MS data from proteomics and metabolomics data sets, comprising technical and biological replicates.

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Optimization of the DNA Purification Protocol for the Thermo Scientific KingFisher Flex and BindIt 3.1 Software
Application Note

Purpose: Optimal quantity and quality of DNA with the magnetic particle based extraction technology. Method: Thermo Scientific KingFisher Flex magnetic particle processor and BindIt® 3.1 Software. Results: By simple optimization of the nucleic acid extraction protocol it is possible to achieve a great yield of high quality DNA.

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Data Acquisition and Analysis of 7-ethoxycoumarin and its Metabolites Using TurboDDS Software in the 500-MS Ion Trap
Application Note

Agilent Technologies

The ion trap is a powerful tool for metabolism studies, due to the MSn capability for the identification of metabolites and structure elucidation of unknown peaks. The TurboDDS™ software on the Varian 500-MS LC Ion Trap eliminates the need to do multiple runs in order to identify metabolites. Once the expected m/z of a metabolite is entered into the method, the 500-MS will automatically look for this m/z and when found, will immediately trigger an MSn experiment.

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