Latest App Notes & Case Studies

While identifying single nucleotide variants (SNVs) and small insertions/deletions (indels) from NGS data has become routine and well established, it is still quite a challenge to accurately detect germline copy-number variations (CNVs) from exome sequencing data as compared to the more conventional methodologies for CNV detection, including comparative genome hybridization arrays.

The Shell Technology Center in Bangalore, India (STCB) is one of the three Technology Centers within Shell that supports both R&D and laboratories at Shell, including non-operating joint venture assets. The analytical laboratory at STCB observed that they were spending a lot of time and energy coordinating services with multiple vendors, each supplying and maintaining highly varied and separate systems.

The specificity of fluorescence microscopy allows researchers to accurately observe and analyze biological processes and structures quickly and easily, even when using thick or large samples. However, out-of-focus fluorescence increases background, reduces contrast and makes accurate image segmentation more challenging.

Setting up a qPCR is a tedious process consisting of multiple pipetting steps. One particularly challenging task is reformatting from microcentrifuge tubes into a 384 well plate, it is time consuming and requires a lot of concentration.

Download this app note to discover a surveillance assay that rill remain effective as new variants emerge whilst offering high sensitivity and capture efficiency.

Traditional methods require highly skilled technicians to run laborious, manual and time-consuming tests on multiple parameters and business growth can mean that these methods become unsustainable; causing a bottleneck that can slow production.

Time is a precious commodity and with ever-increasing regulatory scrutiny, pharmaceutical laboratories are always on the lookout for simple solutions to make their routine tasks easier. Here, we speak with experts to find out how they helping scientists weigh samples in the most efficient yet trusted way to date.

Laboratory information management systems (LIMS) are becoming increasingly important in GMP-regulated environments in order to ensure data integrity and faster working practices.

Download this app note to learn more about data quality and library complexity using next-generation sequencing.

Download this whitepaper to discover how using a cloud ELN can have a transformative impact on your research.