Latest App Notes & Case Studies
App Note / Case Study
Replacing a Legacy LIMS at the Pacific Environmental Science Centre
The Pacific Environmental Science Centre (PESC) had been using a LIMS developed in the 1970s but, with multi-functionality required, covering 105 applications, and with 12 functional areas of the laboratory and around 500,000 tests conducted per year, the system was becoming increasingly more difficult and time-consuming to maintain.
App Note / Case Study
Minimizing Compliance Risk at Regulated Nutrient Manufacturer
Today’s laboratories are struggling to find ways to effectively solve their two most important issues: addressing regulatory compliance, including 21 CFR Part 11, and improving inefficient processes. Fortitech Inc.’s burgeoning task of managing and documenting ingredient blend quality procedures, invoked an initiative to fully automate lab operations.
App Note / Case Study
Qualitative and Quantitative Characterization of the Metabolome, Lipidome, and Proteome of Human Hepatocytes Stably Transfected with Cytochrome P450 2E1 Using Data Independent LC/MS
Drug toxicity is a major reason for the failure of candidate pharmaceuticals during their development. Therefore, it is important to realize the potential for toxicity in a timely fashion. A label-free multi-omics approach has been applied for the analysis of the transfected human hepatocyte cells by implementing LC/HDMSE, providing both qualitative and quantitative information within a single experiment.
App Note / Case Study
TransOmics Informatics Powered by Nonlinear Dynamics
This application note introduces the workflow of TransOmics Informatics Software that has been specifically developed for the larger scale analysis of ion mobility MS data from proteomics and metabolomics data sets, comprising technical and biological replicates.
App Note / Case Study
Optimization of the DNA Purification Protocol for the Thermo Scientific KingFisher Flex and BindIt 3.1 Software
Purpose: Optimal quantity and quality of DNA with the magnetic particle based extraction technology. Method: Thermo Scientific KingFisher Flex magnetic particle processor and BindIt® 3.1 Software. Results: By simple optimization of the nucleic acid extraction protocol it is possible to achieve a great yield of high quality DNA.
App Note / Case Study
Data Acquisition and Analysis of 7-ethoxycoumarin and its Metabolites Using TurboDDS Software in the 500-MS Ion Trap
The ion trap is a powerful tool for metabolism studies, due to the MSn capability for the identification of metabolites and structure elucidation of unknown peaks. The TurboDDS™ software on the Varian 500-MS LC Ion Trap eliminates the need to do multiple runs in order to identify metabolites. Once the expected m/z of a metabolite is entered into the method, the 500-MS will automatically look for this m/z and when found, will immediately trigger an MSn experiment.
App Note / Case Study
SDMS Vision Publisher Facilitating Masslynx and Empower Software Data Capture
As the volume and complexity of research data continues to grow, the use of an electronic format for laboratory record keeping is the key to simple recording and global communication of critical scientific information.
App Note / Case Study
Flexible Lab and Data Management for the Applied Biosystems SOLiD(TM) Next Generation Sequencing System
The Applied Biosystems SOLiDTM system is revolutionizing genetic analysis. Its massively parallel sequencing of clonallyamplified
DNA fragments provides accurate, high-throughput results for growing applications in transcriptomics, epigenomics, and whole genome and targeted resequencing, all in one platform.
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