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Sensitive Signature Peptide Quantification Using Accurate Mass Spectrometry

Sensitive Signature Peptide Quantification Using Accurate Mass Spectrometry
Credit : Istock

Traditional workflows for peptide quantification have been replaced by LC-MS/MS analysis using triple quadrupole mass spectrometers which offer great sensitivity and quantitative performance.

However, accurate mass spectrometry platforms, such as traditional time-of-flight (TOF) systems, often lack sensitivity due to the limited duty cycle in between TOF pulses.

This application note presents a highly sensitive signature peptide quantification workflow using cutting-edge accurate mass spectrometry technology.

Download this application note to explore how to: 

  • Implement a highly sensitive signature peptide quantification workflow 
  • Achieve low-amol/µL level quantification of signature peptides in complex matrices
  • Acquire, process and manage data on a single platform 
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