Building Protein-Protein Interaction Networks with Proteomic and Informatics Tools
News Jun 20, 2011
The systematic characterization of the whole interactomes of different model organisms has revealed that the eukaryotic proteome is highly interconnected. Therefore, biological research is progressively shifting away from classical approaches which focus only on a few proteins towards whole protein interaction networks to describe the relationship of proteins in biological processes. In this mini-review, we survey the most common methods for the systematic identification of protein interactions, and exemplify different strategies for the generation of protein interaction networks.
The article is published online in the Journal of Biological Chemistry and is free to access.
Staphylococcus epidermidis is an ubiquitous colonizer of healthy human skin, but it is also a notorious source of serious nosocomial infections. Now, a new machine learning technique will help predict the risk of developing a serious, and possibly life-threatening S. epidermidis infection.READ MORE
Small imperfections in a wine glass or tiny creases in a contact lens can be tricky to make out, even in good light. In almost total darkness, images of such transparent features or objects are nearly impossible to decipher. But now, engineers at MIT have developed a technique that can reveal these “invisible” objects, in the dark.