Genecards® Create Exciting New Link Between Human Genes and Chemical Reagents from Tocris Bioscience
News Oct 01, 2008
Dr Robert Felix, Tocris’ Product Manager said, “The new ability provided by GeneCards to rapidly associate Tocris’ high quality research compounds with genes and proteins highlights the central importance of chemical tools in the study of the biology of our genes. We expect that this capability will be of great benefit to life scientists and will lead to new avenues of research.”
The powerful GeneCards search engine provides users with concise genomic, proteomic, transcriptomic, genetic and functional information on all known and predicted human genes.
Information featured in GeneCards includes orthologies, disease relationships, mutations and SNPs, gene expression patterns, gene function, pathways, protein-protein interactions, related drugs and compounds, and direct links to Tocris’ comprehensive 'Target files'
A recent introduction to the Tocris website, ‘Target Files’ consist of a concise summary of the biological target, together with links to external sources of genetic and pharmacological information. Tocris products with activity at each target are listed here allowing rapid identification of the most relevant research tools.
Dr. David Warshawsky, Chief Executive Officer of Xennex Inc., the commercial partner of GeneCards, added “We are very pleased about our work with Tocris and are delighted that GeneCards users will have gene-specific access to Tocris’ high quality research compounds. I am confident that offering access to Tocris’ products will help many of our users in academia and industry in their efforts in areas such as basic research and drug discovery.”
In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell’s internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building. This gives researchers a way not only to eliminate a mutated gene sequence, but to influence how the gene is expressed and regulated.
Researchers published today a detailed description of the complete genome of bread wheat, the world's most widely-cultivated crop. This work will pave the way for the production of wheat varieties better adapted to climate challenges, with higher yields, enhanced nutritional quality and improved sustainability.