Labcyte and FIMM Announce a Collaboration Enabling “Real-Time” Science to Advance Personalized Medicine in Cancer Treatments
News Jan 08, 2013
Labcyte Inc. and the Institute for Molecular Medicine Finland (FIMM) are collaborating to further the development of personalized medicine in cancer treatment. Labcyte acoustic liquid handling technology has already revolutionized small-molecule research. Now, FIMM, a European leader in advanced research for new cancer therapies, will apply the technology extensively in its personalized medicine programs.
“FIMM has successfully used Labcyte acoustic liquid handling technology to generate better data and drive down costs in small-molecule screening for the past three years. This collaboration with such a well-regarded institute will facilitate breakthroughs in personalized medicine.”
“FIMM’s groundbreaking use of acoustic liquid handling will demonstrate the technology’s role in genetic research,” said Mark Fischer-Colbrie, CEO of Labcyte. “FIMM has successfully used Labcyte acoustic liquid handling technology to generate better data and drive down costs in small-molecule screening for the past three years. This collaboration with such a well-regarded institute will facilitate breakthroughs in personalized medicine.”
FIMM uses large sample sets with links to detailed patient records and genetic data to discover personalized treatment options at a faster pace.
“We see an enormous potential in expanding our use of Labcyte acoustic dispensing technology to help discover specialized leukemia treatments,” said Professor Olli Kallioniemi, director of FIMM. “This research is based on high-throughput drug sensitivity and resistance testing of leukemic cells taken from patients. This new initiative will bring us closer to the clinic and closer to patients.”
“Our aim is to find alternate treatment options for patients who simultaneously undergo treatment in the clinic,” said Kallioniemi. “We will be doing real-time science, using new scientific insights and technologies to help patients who have failed standard leukemia treatments.”
Increasing its throughput enables FIMM to do more rapid and more efficient testing. Researchers at the Institute hope to learn how leukemia cells ex-vivo respond to various types of drugs, and what the resistance mechanisms are. “Larger trials with samples from acute myeloid leukemia patients who have relapsed under standard treatment may quickly suggest individualized treatment options using existing cancer drugs,” added Kallioniemi. “We’re not saying we can cure leukemia, but for patients who have run out of options, alternative treatments may be available sooner.”
By working with FIMM to utilize acoustic liquid handling in genetics research, Labcyte will continue to expand the application of its technology in bio-marker discovery, single-cell analysis, RT-qPCR, genotyping, siRNA screening, and bio-banking.
“We are excited to be an enabling platform for improving patient care with FIMM,” said Fischer-Colbrie. “It will continue to demonstrate how acoustic liquid handling enhances life science research.”
“This research may be changing the way new and emerging drugs are introduced for patients—it is truly game-changing,” said Kallioniemi. “Labcyte technology is a key enabling platform for this drug-sensitivity testing.”
Computer bits are binary, with a value of 0 or 1. By contrast, neurons in the brain can have all kinds of different internal states, depending on the input that they received. This allows the brain to process information in a more energy-efficient manner than a computer. A new study hopes to bring the two closer together.
MIT researchers have developed a cryptographic system that could help neural networks identify promising drug candidates in massive pharmacological datasets, while keeping the data private. Secure computation done at such a massive scale could enable broad pooling of sensitive pharmacological data for predictive drug discovery.