RURO and Ayrris: Big-Data Lab Management for Production-Scale NGS
News Aug 13, 2013
RURO and Appistry have announced a partnership to deliver integrated solutions for Big-Data Lab Management for Production-Scale NGS.
Automation is a fact of life for modern labs. But effectively managing the increasingly ubiquitous handoffs between humans, instruments, and computers requires ways to expedite and support both the physical work performed in the lab and the associated digital tasks performed by a lab’s computational workers. This is particularly important for labs seeking to provide results and diagnostic insights from data-intensive techniques such as NGS.
The winning combination of RURO’s software used in a variety of laboratory settings and Appistry’s Ayrris big-data computing pipeline creates the data-aware, computationally conscious lab environments.
Smart integration of the Ayrris with LIMS 24/7sets new standards for translational medicine. Customers using the join solution will gain a seamless transition from NGS laboratory workflows into a computational pipeline and back.
It’s a logical integration given the influx of data from NGS. RURO’s LIMS 24/7 is a comprehensive, easy-to-implement laboratory information management system that tracks data associated with all administrative and wet lab processes, from receipt and preparation of samples through running libraries on sequencers. But a LIMS can’t track and expedite data processing and analysis steps, and that’s where Ayrriscomes in. Sitting between sequencers and the applications that interpret and store data, Ayrrisprovides the key big data capabilities labs need to run customer’s pipelines at scale.
Laboratories seeking to implement clinical NGS will gain a continuous pipeline that makes collecting, storing, managing, and routing data simple, reliable, and efficient.
Integrating a LIMS with a robust big-data environment enables laboratories to:
• Establish and maintain a full chain of custody for samples and associated data across the experimental life cycle
• Standardize physical and digital processes to achieve compliance with regulations such as CLIA, HIPAA or Safe Harbor
• Create production-grade workflows necessary for running defined lab workflows at scale
Computer bits are binary, with a value of 0 or 1. By contrast, neurons in the brain can have all kinds of different internal states, depending on the input that they received. This allows the brain to process information in a more energy-efficient manner than a computer. A new study hopes to bring the two closer together.
MIT researchers have developed a cryptographic system that could help neural networks identify promising drug candidates in massive pharmacological datasets, while keeping the data private. Secure computation done at such a massive scale could enable broad pooling of sensitive pharmacological data for predictive drug discovery.
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