We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement
Structure Based Virtual Screening of Anticanerous Polyphenolic Phytocompounds against G-Protein Coupled Receptor and Identification of Potent Antagonist Ligand(S) Through Molecular Docking
News

Structure Based Virtual Screening of Anticanerous Polyphenolic Phytocompounds against G-Protein Coupled Receptor and Identification of Potent Antagonist Ligand(S) Through Molecular Docking

Structure Based Virtual Screening of Anticanerous Polyphenolic Phytocompounds against G-Protein Coupled Receptor and Identification of Potent Antagonist Ligand(S) Through Molecular Docking
News

Structure Based Virtual Screening of Anticanerous Polyphenolic Phytocompounds against G-Protein Coupled Receptor and Identification of Potent Antagonist Ligand(S) Through Molecular Docking

Read time:
 

Want a FREE PDF version of This News Story?

Complete the form below and we will email you a PDF version of "Structure Based Virtual Screening of Anticanerous Polyphenolic Phytocompounds against G-Protein Coupled Receptor and Identification of Potent Antagonist Ligand(S) Through Molecular Docking"

First Name*
Last Name*
Email Address*
Country*
Company Type*
Job Function*
Would you like to receive further email communication from Technology Networks?

Technology Networks Ltd. needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy

Abstract
Design of potential drug-like candidates for cancer is of interest in recent years. We used 60 compounds which are known to have the potential to down regulate Nuclear Factor kappaB (NFκB) for this study. The compounds were assessed for Lipinski's RO5 and ADMET properties. Allixin, anethole, capsaicin, linearol and syringic acid satisfied both Lipinski's RO5 and ADMET properties. These compounds showed strong molecular interaction with receptor GPCR55 indicating they have ability to block GPCR55. Thus, their role in anticellular proliferation and induction of apoptosis is implied.

The article is published online in Bioinformation and is free to access.

Advertisement