Exploiting Polypharmacology in Precision Oncology: Identification of Differential Kinase Off-targets Among Clinical PARP Inhibitors

Poster   Nov 08, 2017

 
Exploiting Polypharmacology in Precision Oncology: Identification of Differential Kinase Off-targets Among Clinical PARP Inhibitors
 
View Poster

Dr. Albert A. Antolin, Dr. Jordi Mestres, Prof. Paul Workman and Dr. Bissan Al-Lazikani

 
 

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License

 
View Poster
 
 
 

OTHER POSTERS

Development and Assessment of Non-Infected and Infected Skin Models Using MALDI-MSI

Poster

Infections have detrimental effects on wound healing leading to chronic wound formation. The use of labskin,a living skin model, in combination with mass spectrometry imaging, provides a good model for assessing wound healing factors.

READ MORE

Bioluminescent Assay for GTPases Allows Measurement of GTPase, GAP and GEF Activities

Poster

We have developed a homogenous bioluminescent assay (GTPase-Glo) system to analyze these proteins in a simple, convenient “add-mix-read” format.

READ MORE

Validation of an Image-Based 3D Natural Killer Cell Mediated Cytotoxicity Assay

Poster

Here we describe a novel 3D NK cell mediated cytotoxicity (CMC) assay.

READ MORE

 

Comments | 0 ADD COMMENT

Like what you just read? You can find similar content on the communities below.

Cancer Research Drug Discovery Proteomics & Metabolomics

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE