TMT Quantification for Shotgun Proteomics: TIMS-QTOF Powered by PASEF

Poster May 31, 2019

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Matt Willetts, Shourjo Ghose, Heiner Koch, Scarlet Koch, Markus Lubeck, Gary Kruppa.

This poster evaluates the performance of ‘timsTOF Pro’ a unique dual trapped ion mobility spectrometer (TIMS) coupled to a QTOF for the analysis of isobaric labelling experiments.

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How TIMS provides an additional dimension of separation and high peak capacity
Why the timsTOF Pro instrument is well suited to isobaric labelled quantitation experiments
How to achieve near 100% duty cycle for shotgun proteomics

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License

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