Agilent Technologies Introduces Bioinformatics Software Providing Systems-Level Microarray Analysis
Product News Sep 23, 2008
Agilent Technologies Inc. has introduced Agilent GeneSpring GX 10.0, the next generation of Agilent’s flagship gene expression bioinformatics platform.
GeneSpring GX, considered the gold standard of desktop gene expression analysis, now offers tools for systems-level data interpretation and pathway analysis, enabling scientists to attain a new level of insight into the underlying mechanism of disease or biological process.
“We developed this new revision of GeneSpring GX to address the growth of systems-level studies in functional genomics research,” said Bruce von Herrmann, Agilent vice president and general manager, Software and Informatics Division. “GeneSpring has always been excellent at gene expression data analysis. Now, it has evolved into an integrated software package that helps scientists discover the relationship between the data and the biological events occurring in their samples.”
GeneSpring GX has earned a solid reputation among gene-expression biologists, with more than 4,400 references in Google Scholar, including more than 1,600 in peer-reviewed publications. As systems-level studies become more prevalent in genomics research, GeneSpring GX 10.0 adds visualization and analysis tools for applications including alternative splicing, miRNA expression and real-time PCR.
To get more insight into the underlying mechanism of disease, GeneSpring now has pathway analysis capabilities. By providing a database of gene product interactions, scientists can build biological interaction networks from their genes of interest.
GeneSpring also provides statistical tools to detect significant changes in miRNA abundance, and integrates TargetScan miRNA gene-target information to determine the biological consequences of detected changes. Additionally, to facilitate validation of microarray experiments, GeneSpring GX 10.0 supports analysis of real-time PCR data.
To support enterprise functional genomics data-analysis needs, Agilent offers GeneSpring Workgroup, a client-server application with GeneSpring GX as the data-analysis engine providing central and secure storage for GeneSpring data and analysis results.
The latest version of GeneSpring GX arises from the collaboration established in August 2007 between Agilent and Strand Life Sciences of Bangalore, India.