Bruker Introduces CMC-assist

At Pittcon 2012, Bruker Corporation presents CMC-assistTM, a new software tool that provides routine NMR users with seamless support in their daily workflow of spectral interpretation. Delivering support where it’s needed CMC-assist assigns the NMR signals to structural characteristics, conducts a structural consistency assessment and provides a spectral analysis. These results are collected in compact reports with just the right level of content for enabling an easy transfer of information into publications, lab journals or patent applications.

With CMC-assist routine NMR users, as well as occasional NMR users, can now benefit from a highly efficient tool for spectral interpretation. CMC-assist enables complex analysis of 1D 1H NMR datasets, thus covering the most commonly experimental approaches in industry and academics. Its highly innovative analysis algorithm performs on-the-fly, fully automated spectra interpretation based on human-logic emulation technology. Solvent resonances and impurities are detected and assigned, and where a structural proposal is provided by the user, CMC-assist performs an automatic consistency check and delivers a full spectral assignment. Finally, when a reference dataset has been provided, the analysis procedure will automatically determine the concentration of the sample.

CMC-assist is aimed at improving throughput and efficiency for NMR users in their analysis of small molecule proton NMR data. In addition, CMC-assist features an uncomplicated user interface that benefits novice NMR users by enabling them to sidestep some of NMR’s steep learning curve, achieved by grouping all user actions by area of application, and ordering of the native workflow by importance and complexity. The user has optimal control over all steps of the analysis, with the added convenience of being able to manually refine the automatically generated results, if desired.    To be able to realize this feature, Bruker has developed an innovative workflow oriented process enabling the user to work with spectra and chemical structures at the same time, allowing complex reports of varying depths of information to be generated by a mouse click.

Not only will CMC-assist ease the workload at any chemist’s off-line workstation, but through seamless integration with Bruker’s latest NMR software releases TopSpinTM and IconNMRTM, direct integration with the unique and truly continuous workflow Fast Lane NMRTM is possible, covering all steps from data acquisition to processing, to analysis and finally, to supervised report generation.

“CMC-assist algorithms combine the latest progress in emulating human logic with Bruker’s proven experience in spectra processing power and renowned strength in graphical interfaces. As a result we now offer our customers a great tool to increase their efficiency and to incorporate NMR in the daily analytical workflow”, commented Dr. Till Kühn, Product Manager at Bruker BioSpin for small molecule applications.