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Ready To Travel Inside A Living Cell As Never Before? Try! Steve Will Guide You!

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Nanolive SA proudly announces the release of an off-line version of STEVE. “Starting from today, scientists, Medical Doctors and students all around the world will be enabled to travel inside 3D cells in full color by simply downloading STEVE on their laptop” declares Dr. Yann Cotte, CEO and co-founder of Nanolive SA.

Nanolive SA is a Swiss start-up company, based at Innovation Park in Lausanne, which is developing a revolutionary microscope (and a revolutionary software) able to image and digitally stain living cells in 3D without any sample preparation and in real-time. The company, which has already received more than 45 pre-orders (with partial up-front payments), is planning the market entry for this summer.

The value measured by the 3D Cell Explorer is not fluorescence intensity of an exogenous molecule like with most optical microscopes. In contrast, Nanolive’s technology detects the physical refractive index of the different cell parts with resolution far beyond the diffraction limit (see Nobel prize 2014 for chemistry). As the Nanolive’s microscope, the 3D Cell Explorer, can be handled with without special training, the company has developed unique software called STEVE.

To mark and label certain parts of the measured cells in 3D, the software allows the user to “virtual brush” and digitally “paint” the part of a cell based on their physical properties (called refractive index). STEVE will automatically define all regions with same refractive index characteristics (different organelles have different optical properties) and digitally stain them with the same color. This process is quantitative and can be applied for a limitless amount of colors. Changes to digital stains are shown in real time in both 2D and 3D views. Stains panels can be constantly modified by the user, saved and reused for other cells of the same line.

For additional support, Nanolive provides a getting started video and getting started document.