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Plasmid editor interface showing original and modified vectors with design inputs and a DNA sequence at the bottom
Credit: Sapio Sciences


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Sapio ELN (Electronic Lab Notebook)

Sapio ELN (Electronic Lab Notebook)
Credit: Sapio Sciences


Sapio ELN is a no-code, AI-native Electronic Lab Notebook built for real scientific work. It supports structured and free-form experiment design, integrates seamlessly with LIMS and SDMS, and includes built-in scientific tools and an AI assistant to accelerate discovery.

Key benefits of Sapio ELN:
- Modern, science-aware Electronic Lab Notebook (ELN) for structured and flexible experimental documentation
- AI-native assistant (Sapio ELaiN) to automate tasks, generate code, and provide instant access to experiment data
- Reusable experiment templates and protocol libraries for consistent and efficient setup
- Integrated molecular biology toolkit for CRISPR workflows, plasmid design, PCR, and genome browsing
- Real-time collaboration with version control and shared scientific objects
- Seamless data integration with Sapio LIMS and SDMS for traceability and compliance
- Built-in visual analytics and interactive widgets to simplify data interpretation
Configurable for research, diagnostics, stability studies, and manufacturing documentation

Modern, science-aware ELN for structured and flexible documentation
Sapio ELN supports both structured workflows and open-format notes, giving scientists the flexibility to capture experiments their way. Whether designing multi-step research processes or jotting down observations, users can build workflows or document experiments with structured fields, free text, sketches, or embedded data.

AI-native assistant (Sapio ELaiN) for automation and insight
Sapio ELaiN, the ELN’s built-in science-aware AI assistant, enables researchers to interact with the system using natural language. Scientists can generate templates, search for data, analyze results, or write simple code with a chat-like interface—no programming expertise required.

Reusable templates and protocols to streamline setup
Researchers can create and reuse experiment templates that standardize workflows across teams and projects. These templates ensure consistency in data capture, minimize manual errors, and speed up the time it takes to begin new experiments.

Integrated molecular biology toolkit for advanced experimentation
The ELN includes native tools for CRISPR guide design, plasmid construction, compound modeling, genome browsing, and PCR primer design—making it an ideal solution for molecular biology, genetic engineering, and biotech workflows.

Real-time collaboration and shared scientific objects
Multiple users can work on experiments simultaneously, with features like inline commenting, version control, and co-authoring. Shared scientific objects such as protocols, materials, and templates foster collaboration across teams and locations.

Seamless integration with LIMS and SDMS for full traceability
As part of the unified Sapio Platform, the ELN connects directly with LIMS and SDMS modules. Experiment data links back to sample records, instrument files, and metadata, giving scientists complete context and traceability without manual reentry.

Built-in analytics and visual tools for immediate insight
Sapio ELN includes graphing, statistical calculations, flow cytometry visualization, and interactive tables that help researchers understand data in context. These built-in tools reduce reliance on external software and accelerate the analysis cycle.

Configurable for diverse scientific domains and compliance needs
Whether documenting biopharma research, clinical workflows, in vivo studies, or regulated stability testing, Sapio ELN adapts to the needs of any lab. It supports compliance with GxP, 21 CFR Part 11, and other industry standards through secure, auditable workflows.


About Sapio Sciences
Sapio Sciences is a technology company that develops software to support drug research and discovery processes. Founded by Kevin Cramer, Sapio Sciences has developed software products for laboratory operations, particularly in biotechnology and chemistry.
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