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Twist Oligo Pools for High-Throughput Screens

Twist Oligo Pools for High-Throughput Screens


Oligo pools are utilized in many applications including generation of CRISPR guide RNA (sgRNA) libraries, peptide and protein screens, and high-throughput reporter assays. Accuracy and uniformity of oligo synthesis are critical to ensure high quality oligo libraries are built and screens are precisely targeted.

Twist Oligo Pools are highly diverse collections of single-stranded oligonucleotides synthesized using our silicon-based DNA writing technology. Our synthesis platform enables massively parallel production of hundreds of thousands of high-quality, accurate oligos per run, allowing the generation of complex and diverse CRISPR screening sgRNA libraries for precision gene editing and maximized screening efficiency.

Due to the sheer scale of our DNA synthesis capability, there are virtually no limitations to the number of unique oligos that can be assembled into a pool. Don't restrict the outcome of your application—order Oligo Pools tailored precisely to your experiment.  


About Twist Bioscience
Twist Bioscience is a synthetic biology company that has developed a proprietary silicon-based manufacturing process for the production of synthetic DNA. Twist Bioscience works in the service of customers who are changing the world for the better in fields such as medicine, agriculture, industrial chemicals and data storage.
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