bit.bio
bit.bio is an award-winning human synthetic biology company whose mission is to code cells for novel cures. They have developed an end-to-end platform for the creation of any human cell type. With their cutting-edge and patent-protected opti-ox™ precision cell programing technology, bit.bio can deterministically program human induced pluripotent stem cells (iPSCs) into a chosen cell identity with unprecedented biological consistency at an industrial scale and approximately 10 times faster than conventional methods. Their platform has the potential to unlock a new generation of medicines.
Latest bit.bio Content
Webinar
Human iPSC-Based Models of Glial Cells for Studying Neurodegenerative Disease
On-Demand
The increasing implication of glial cells in neurodegenerative diseases makes them an appealing addition to iPSC-based model systems for investigating disease mechanisms.
Industry Insight
Exploring Human iPSC-Derived Astrocytes for Advancing CNS Research
In this interview, Dr. Mitzy Rios de Anda sheds light on the potential of human iPSC-derived astrocytes, discussing how these cells are reshaping our understanding of the brain, neurological diseases and therapeutic development.
Video
Leveraging Human iPSC-Derived Astrocytes for Neurological Research and Therapy
In this episode we speak with bit.bio about astrocytes and how bit.bio's innovative technology is transforming research in this area.
Webinar
Powering a New Generation of Physiologically-Relevant CRISPR Screens
On-Demand
CRISPR-Cas9 gene editing is an essential functional genomics tool, facilitating the cataloging of genomic variations linked to human diseases for the discovery and validation of novel drug targets.
Product
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ioAstrocytes - Human iPSC-Derived Astrocytes
ioAstrocytes offer a solution to researchers who are searching for easy-to-use, highly characterised human cells that are designed for co-culture and effectively recapitulate astrocyte functions within CNS models in vitro
App Note / Case Study
Studying the Link Between Cell Migration and Neurodegenerative Disease With iPSC-derived Microglia
In this application note, researchers from Medicines Discovery Catapult (MDC) evaluated the suitability of iPSC-derived microglia as a model for studying the mechanics of microglia activation, shedding light on their role in neurodegeneration and the potential for therapeutic targets.
App Note / Case Study
Improving Physiological Relevance in Neurological Disease Drug Development
This case study explores the use of human iPSC-derived microglial cells as a more reliable model for neurobiological drug development.
Poster
Improving Physiological Relevance in Functional Genomics Screens
This poster describes the use of CRISPR-ready iPSCs, which are engineered to constitutively express Cas9, enabling the rapid generation of high-efficiency gene knockouts and CRISPR screens in a functional, physiologically relevant cell background.
Video
How To Accelerate Research and Drug Discovery in Motor Neuron Disease: A Deep Dive Into Precision Reprogrammed Human iPSC-Derived Motor Neurons
In the Teach Me in 10 video, Dr. Marcos Herrera-Vaquero, bit.bio discusses motor neurons and their critical role in Motor Neuron Diseases (MNDs) such as amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA).
App Note / Case Study
Speeding Up Neuroscience Research
Delve into this case study to explore how a research lab at King’s College London used hiPSC-derived neurons to shed light on synaptic biology and potential treatments for psychiatric conditions.
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