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Crown Bioscience

Crown Bioscience is a global contract research organization providing discovery, preclinical and translational platforms and services to advance oncology and immuno-oncology. They are known for their high-quality and expansive in vivo, in vitro, and ex vivo preclinical models, and partner with their clients to quantify the efficacy and pharmacological profile of their drug candidate(s) before they move into the clinic. Crown Bioscience aims to deliver superior drug candidates to ensure that patients get the right treatment at the right time.

Latest Crown Bioscience Content


Pan-cancer Assay-ready Organoid Drug Screening With Robust, Reproducible, and Clinically-relevant Output

In this episode we discuss a new drug screening platform, and assay-ready organoid platform, that allows for high throughput drug screening assays and large panel screens with short timelines.

MS-based Proteomics: 4D-DIA Proteomics & 4D Phosphoproteomics

Crown Bioscience offers next generation ion mobility-mass spectrometry (IM-MS)-based-proteomics services to global clients.

This will allow clients to assess the biological function of proteins for understanding signaling mechanisms within cells as well as specific biomarkers to diseases, and systematically assess quantitative differences in protein profiles of distinct samples for biomedical and clinical research.

Quantitative Proteomics Services To Upgrade Your Research

Proteomics provides crucial insights into cell signaling and disease mechanisms for biomedical and clinical research. Nevertheless, traditional LC-MS/MS methods have limitations in sensitivity, reproducibility and scalability within proteomics applications.
Illustration of a cell culture plate with various organoids linking to the area of the human body they are from.

An Introduction to Organoids, Organoid Creation, Culture and Applications

Organoids have revolutionized biological and medical research and proven to be excellent substitutes for animal models in preclinical studies. Here, we discuss what organoids are and how they have been developed over the years to become popular research tools.
High-Throughput and High-Content Screening in Organoids and 3D Models With Michiel Fokkelman content piece image

High Throughput and High Content Screening in Organoids and 3D Models at Crown Bioscience With Michiel Fokkelman

In this episode, Lucy Lawrence and Michiel Fokkelman will discuss the concept of high content imaging of 3D-cultured organoids in combination with high throughput screening as a service for drug discovery and pre-clinical drug development.
Teach Me in 10 Industry content piece image

Teach Me in 10 Industry

Our Teach Me in 10 episodes are either technology, product or service focused. We invite you to explore the further reading and resources provided in the video description if you want to learn more about the content shared in the video – it's as easy as that.